期刊
MONATSHEFTE FUR CHEMIE
卷 141, 期 3, 页码 351-356出版社
SPRINGER WIEN
DOI: 10.1007/s00706-010-0266-8
关键词
Phosphonato esters; Diastereoselective synthesis; Karplus equation; Biological activity
资金
- Research Council of the University of Sistan and Baluchestan
Synthesis of five phosphonato esters has been accomplished via reaction between dimethyl acetylenedicarboxylate and triphenyl phosphite in the presence of biological compounds such as theophylline, 4-hydroxypyrimidine, 2H-3,1-benzoxazine-2,4(1H)-dione, 2-chloroaniline, or 3-nitroaniline at ambient temperature. The configuration of the compounds was determined on the basis of coupling constants emerging from the Karplus equation.
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