期刊
MONATSHEFTE FUR CHEMIE
卷 140, 期 1, 页码 45-47出版社
SPRINGER WIEN
DOI: 10.1007/s00706-008-0008-3
关键词
Chromene; Multicomponent reaction; N,N-Dimethylaminoethylbenzyldimethylammonium chloride; Solvent-free condition
资金
- National Natural Science Foundation of China [20672046]
- Guangdong Natural Science Foundation [04010458]
A simple, clean, and environmentally benign three-component process to the synthesis of 2-amino-4H-chromenes using N,N-dimethylaminoethylbenzyldimethylammonium chloride, [PhCH2Me2N+CH2CH2NMe2]Cl-, as an efficient catalyst under solvent-free condition is described. A wide range of aromatic aldehydes easily undergo condensations with alpha-naphthol and malononitrile under solvent-free condition to afford the desired products of good purity in excellent yields. Taking into account environmental and economical considerations, the protocol presented here has the merits of environmentally benign, simple operation, convenient work-up and good yields. Furthermore, the catalyst can be easily recovered and reused for at least five cycles without losing its activities.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据