期刊
MONATSHEFTE FUR CHEMIE
卷 139, 期 4, 页码 447-457出版社
SPRINGER WIEN
DOI: 10.1007/s00706-008-0895-3
关键词
RNA folding kinetics; Co-transcriptional folding; folding pathway; metastable structures
The term RNA folding is often used synonymously with the prediction of equilibrium structures. Yet many RNAs function thanks to their ability to undergo structural changes. In this contribution we present a systematic overview of existing approaches to the prediction of RNA folding kinetics, and in particular discuss the strengths and limitations of each method.
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