期刊
MOLECULES
卷 19, 期 2, 页码 1411-1421出版社
MDPI AG
DOI: 10.3390/molecules19021411
关键词
ultrasonic-assisted extraction; mangiferin; mango leaves; response surface methodology
资金
- National Natural Science Foundation of China [81302416]
- Scientific Research Foundation of Guangdong Medical College [B2012009]
Mangiferin is a xanthone widely distributed in higher plants showing antioxidative, antiviral, anticancer, antidiabetic, immunomodulatory, hepatoprotective and analgesic effects. In the present study, an ultrasonic-assisted extraction method was developed for the effective extraction of mangiferin from mango leaves. Some parameters such as ethanol concentration, liquid-to-solid ratio, extraction temperature, and extraction time were optimized by single-factor experiment and response surface methodology. The optimal extraction conditions were 44% ethanol, the liquid-to-solid ratio was 38: 1, and extraction for 19.2 min at 60 degrees C under ultrasound irradiation of 200 W. Under optimal conditions, the yield of mangiferin was 58.46 +/- 1.27 mg/g. The results obtained are helpful for the full utilization of mango leaves, and also indicated that ultrasonic-assisted extraction is a very useful method for the extraction of mangiferin from plant materials.
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