期刊
MOLECULES
卷 18, 期 5, 页码 5306-5316出版社
MDPI
DOI: 10.3390/molecules18055306
关键词
Pulsatilla koreana; triterpene saponin; Meloidogyne incognita; nematicidal activity
资金
- Priority Research Center Program through the National Research Foundation of Korea (NRF) [2009-0093815]
- Ministry of Education, Science and Technology, Korea
Pulsatilla koreana, a species endemic to Korea, is an important herb used in traditional medicine to treat amoebic dysentery and malaria. In the present study, 23 oleanane-type triterpenoid saponins 1-23 and eight lupane-type triterpenoid saponins 24-31 were isolated from the roots of P. koreana. Their structures were elucidated on the basis of spectroscopic data. The methanol extract and isolated compounds were next assessed for nematicidal activity against the root-knot nematode ( Meloidogyne incognita). The methanol extract showed strong nematicidal activity after 48 h, with a LC50 value of 92.8 mu g/mL. Compounds 2, 5, 9, 20, and 21 showed significant effects, with LC50 values ranging from 70.1 to 94.7 mu g/mL after 48 h. These results suggest that triterpenoid saponins from P. koreana should be explored as potential natural nematicides for developing new agents to control root-knot nematode disease.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据