4.6 Article

Synthesis and Antibacterial Evaluation of Some Novel Imidazole and Benzimidazole Sulfonamides

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MOLECULES
卷 18, 期 10, 页码 11978-11995

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MDPI
DOI: 10.3390/molecules181011978

关键词

sulfonamide; 4-methylbenzenesulfonamide; 4-nitrobenzenesulfonamide; 4-methoxybenzenesulfonamide; imidazole; benzimidazole; antibacterial activity

资金

  1. University of Malaya by HIR UM-MOHE [F00004-21001, FP001/2010A, UMRG RG233-12AFR]

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Several new substituted sulfonamide compounds were synthesized and their structures were confirmed by H-1-NMR, C-13-NMR, FT-IR, and mass spectroscopy. The antibacterial activities of the synthesized compounds were screened against standard strains of six Gram positive and four Gram negative bacteria using the microbroth dilution assay. Most of the compounds studied showed promising activities against both types of bacteria.

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