期刊
MOLECULES
卷 18, 期 12, 页码 14892-14919出版社
MDPI
DOI: 10.3390/molecules181214892
关键词
Gymnema sylvestre; triterpenoids; oleanes; pharmacological activities; phytochemistry
资金
- AIPRAS Onlus (Associazione Italiana per la Promozione delle Ricerche sull'Ambiente e la Salute umana)
Gymnema sylvestre R. Br., one of the most important medicinal plants of the Asclepiadaceae family, is a herb distributed throughout the World, predominantly in tropical countries. The plant, widely used for the treatment of diabetes and as a diuretic in Indian proprietary medicines, possesses beneficial digestive, anti-inflammatory, hypoglycemic and anti-helmentic effects. Furthermore, it is believed to be useful in the treatment of dyspepsia, constipation, jaundice, hemorrhoids, cardiopathy, asthma, bronchitis and leucoderma. A literature survey revealed that some other notable pharmacological activities of the plant such as anti-obesity, hypolipidemic, antimicrobial, free radical scavenging and anti-inflammatory properties have been proven too. This paper aims to summarize the chemical and pharmacological reports on a large group of C-4 gem-dimethylated pentacyclic triterpenoids from Gymnema sylvestre.
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