期刊
MOLECULES
卷 14, 期 5, 页码 1725-1746出版社
MDPI
DOI: 10.3390/molecules14051725
关键词
DNA; RNA; photointercalators; fluorescence; rational design; therapy; cancer
资金
- FAPDF
- CAPES
- CNPq
In the present overview, we describe the bases of intercalation of small molecules (cationic and polar neutral compounds) in DNA. We briefly describe the importance of DNA structure and principles of intercalation. Selected syntheses, possibilities and applications are shown to exemplify the importance, drawbacks and challenges in this pertinent, new, and exciting research area. Additionally, some clinical applications (molecular processes, cancer therapy and others) and trends are described.
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