期刊
MOLECULES
卷 13, 期 10, 页码 2557-2569出版社
MDPI
DOI: 10.3390/molecules13102557
关键词
Quinazolin-4-(3H)-ones; piperazines; chloroacetamide; anticonvulsant activity
A number of 3-substituted-2-(substituted-phenoxymethyl) quinazolin-4(3H)-one derivatives have been synthesized. Their structures have been elucidated on the basis of elemental analyses and spectroscopic studies (IR, H-1-NMR, MS). A preliminary evaluation of the anticonvulsant properties of the prepared compounds has indicated that some of them exhibit moderate to significant activity, compared to a diazepam standard.
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