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N. M. Kemppainen et al.
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Oskar Hansson et al.
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M. Bibl et al.
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J. J. Kulstad et al.
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M Bibl et al.
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LM Wilson et al.
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Anna M. Barron et al.
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S Lesné et al.
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I Blasko et al.
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J Ghiso et al.
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