相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。miR-200c Inhibits Melanoma Progression and Drug Resistance through Down-Regulation of Bmi-1
Shujing Liu et al.
AMERICAN JOURNAL OF PATHOLOGY (2012)
Epigenetic Regulation of Cancer Stem Cell Genes in Triple-Negative Breast Cancer
Naofumi Kagara et al.
AMERICAN JOURNAL OF PATHOLOGY (2012)
MicroRNA-320a suppresses human colon cancer cell proliferation by directly targeting β-catenin
Jian-Yong Sun et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2012)
EZH2 inhibition: targeting the crossroad of tumor invasion and angiogenesis
Francesco Crea et al.
CANCER AND METASTASIS REVIEWS (2012)
Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment
Douglas Hanahan et al.
CANCER CELL (2012)
Curcumin Analogue CDF Inhibits Pancreatic Tumor Growth by Switching on Suppressor microRNAs and Attenuating EZH2 Expression
Bin Bao et al.
CANCER RESEARCH (2012)
MicroRNA-1826 directly targets beta-catenin (CTNNB1) and MEK1 (MAP2K1) in VHL-inactivated renal cancer
Hiroshi Hirata et al.
CARCINOGENESIS (2012)
Hypoxia-induced mixed-lineage leukemia 1 regulates glioma stem cell tumorigenic potential
J. M. Heddleston et al.
CELL DEATH AND DIFFERENTIATION (2012)
Haploinsufficiency of Dnmt1 impairs leukemia stem cell function through derepression of bivalent chromatin domains
Jennifer J. Trowbridge et al.
GENES & DEVELOPMENT (2012)
MicroRNA 34c Gene Down-regulation via DNA Methylation Promotes Self-renewal and Epithelial-Mesenchymal Transition in Breast Tumor-initiating Cells
Fengyan Yu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
The evolving concept of cancer and metastasis stem cells
Irene Baccelli et al.
JOURNAL OF CELL BIOLOGY (2012)
ZEB1 drives prometastatic actin cytoskeletal remodeling by downregulating miR-34a expression
Young-Ho Ahn et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Defining the mode of tumour growth by clonal analysis
Gregory Driessens et al.
NATURE (2012)
A restricted cell population propagates glioblastoma growth after chemotherapy
Jian Chen et al.
NATURE (2012)
Hepatic stem cells and transforming growth factor β in hepatocellular carcinoma
Avijit Majumdar et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2012)
β-Catenin/LEF1 transactivates the microRNA-371-373 cluster that modulates the Wnt/β-catenin-signaling pathway
A-D Zhou et al.
ONCOGENE (2012)
Loss of Let-7 Up-Regulates EZH2 in Prostate Cancer Consistent with the Acquisition of Cancer Stem Cell Signatures That Are Attenuated by BR-DIM
Dejuan Kong et al.
PLOS ONE (2012)
Antagonism of miR-21 Reverses Epithelial-Mesenchymal Transition and Cancer Stem Cell Phenotype through AKT/ERK1/2 Inactivation by Targeting PTEN
Mingli Han et al.
PLOS ONE (2012)
Lineage Tracing Reveals Lgr5+ Stem Cell Activity in Mouse Intestinal Adenomas
Arnout G. Schepers et al.
SCIENCE (2012)
miR-21 Is a Promising Novel Biomarker for Lymph Node Metastasis in Patients with Gastric Cancer
Yuejuan Xu et al.
GASTROENTEROLOGY RESEARCH AND PRACTICE (2012)
被撤回的出版物: Ectopic expression of the histone methyltransferase Ezh2 in haematopoietic stem cells causes myeloproliferative disease (Retracted article. See vol. 8, Art no 14005, 2017)
A. Herrera-Merchan et al.
NATURE COMMUNICATIONS (2012)
MicroRNA expression profile of colon cancer stem-like cells in HT29 adenocarcinoma cell line
Huanle Zhang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
Breast cancer resistance protein BCRP/ABCG2 regulatory microRNAs (hsa-miR-328, -519c and -520h) and their differential expression in stem-like ABCG2+ cancer cells
Xin Li et al.
BIOCHEMICAL PHARMACOLOGY (2011)
EZH2 Promotes Expansion of Breast Tumor Initiating Cells through Activation of RAF1-β-Catenin Signaling
Chun-Ju Chang et al.
CANCER CELL (2011)
DCAMKL-1 Regulates Epithelial-Mesenchymal Transition in Human Pancreatic Cells through a miR-200a-Dependent Mechanism
Sripathi M. Sureban et al.
CANCER RESEARCH (2011)
Frizzled 4 Regulates Stemness and Invasiveness of Migrating Glioma Cells Established by Serial Intracranial Transplantation
Xun Jin et al.
CANCER RESEARCH (2011)
Novel Histone Demethylase LSD1 Inhibitors Selectively Target Cancer Cells with Pluripotent Stem Cell Properties
Jing Wang et al.
CANCER RESEARCH (2011)
EMT and Stem Cell-Like Properties Associated with miR-205 and miR-200 Epigenetic Silencing Are Early Manifestations during Carcinogen-Induced Transformation of Human Lung Epithelial Cells
Carmen S. Tellez et al.
CANCER RESEARCH (2011)
Cancer epigenetics: linking basic biology to clinical medicine
Hsing-Chen Tsai et al.
CELL RESEARCH (2011)
The Intestinal Stem Cell Signature Identifies Colorectal Cancer Stem Cells and Predicts Disease Relapse
Anna Merlos-Suarez et al.
CELL STEM CELL (2011)
Targeting Notch signalling by the conserved miR-8/200 microRNA family in development and cancer cells
Diana M. Vallejo et al.
EMBO JOURNAL (2011)
Immune microenvironments in solid tumors: new targets for therapy
Stephen L. Shiao et al.
GENES & DEVELOPMENT (2011)
Epigenetic regulation of signaling pathways in cancer: Role of the histone methyltransferase EZH2
Daisy P. F. Tsang et al.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2011)
MicroRNA-200c attenuates tumour growth and metastasis of presumptive head and neck squamous cell carcinoma stem cells
Wen-Liang Lo et al.
JOURNAL OF PATHOLOGY (2011)
Pharmacologic disruption of Polycomb Repressive Complex 2 inhibits tumorigenicity and tumor progression in prostate cancer
Francesco Crea et al.
MOLECULAR CANCER (2011)
Ovarian Cancer Stem Cell-Like Side Populations Are Enriched Following Chemotherapy and Overexpress EZH2
Sian Rizzo et al.
MOLECULAR CANCER THERAPEUTICS (2011)
p53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs
Chun-Ju Chang et al.
NATURE CELL BIOLOGY (2011)
The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44
Can Liu et al.
NATURE MEDICINE (2011)
Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression
Mina J. Bissell et al.
NATURE MEDICINE (2011)
Genome-scale epigenetic reprogramming during epithelial-to-mesenchymal transition
Oliver G. McDonald et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2011)
MicroRNA-221/222 confers breast cancer fulvestrant resistance by regulating multiple signaling pathways
X. Rao et al.
ONCOGENE (2011)
miR-495 is upregulated by E12/E47 in breast cancer stem cells, and promotes oncogenesis and hypoxia resistance via downregulation of E-cadherin and REDD1
W. W. Hwang-Verslues et al.
ONCOGENE (2011)
Identifying the cellular origin of squamous skin tumors
Gaelle Lapouge et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Defining the origins of Ras/p53-mediated squamous cell carcinoma
Andrew C. White et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Hypoxia Increases the Expression of Stem-Cell Markers and Promotes Clonogenicity in Glioblastoma Neurospheres
Eli E. Bar et al.
AMERICAN JOURNAL OF PATHOLOGY (2010)
Identification of a novel putative pancreatic stem/progenitor cell marker DCAMKL-1 in normal mouse pancreas
Randal May et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2010)
A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2α
Sascha Seidel et al.
BRAIN (2010)
The guardians of the genome (p53, TA-p73, and TA-p63) are regulators of tumor suppressor miRNAs network
Lakshmanane Boominathan
CANCER AND METASTASIS REVIEWS (2010)
MicroRNA-21 in Pancreatic Cancer: Correlation with Clinical Outcome and Pharmacologic Aspects Underlying Its Role in the Modulation of Gemcitabine Activity
Elisa Giovannetti et al.
CANCER RESEARCH (2010)
Coexpression of Oct4 and Nanog Enhances Malignancy in Lung Adenocarcinoma by Inducing Cancer Stem Cell-Like Properties and Epithelial-Mesenchymal Transdifferentiation
Shih-Hwa Chiou et al.
CANCER RESEARCH (2010)
Double-Negative Feedback Loop between Reprogramming Factor LIN28 and microRNA let-7 Regulates Aldehyde Dehydrogenase 1-Positive Cancer Stem Cells
Xiaojun Yang et al.
CANCER RESEARCH (2010)
The Myc-miR-17∼92 Axis Blunts TGFβ Signaling and Production of Multiple TGFβ-Dependent Antiangiogenic Factors
Michael Dews et al.
CANCER RESEARCH (2010)
被撤回的出版物: Gemcitabine Sensitivity Can Be Induced in Pancreatic Cancer Cells through Modulation of miR-200 and miR-21 Expression by Curcumin or Its Analogue CDF (Retracted article. See vol. 78, pg. 5466, 2018)
Shadan Ali et al.
CANCER RESEARCH (2010)
Involvement of epigenetically silenced microRNA-181c in gastric carcinogenesis
Yutaka Hashimoto et al.
CARCINOGENESIS (2010)
MicroRNA-34a suppresses invasion through downregulation of Notch1 and Jagged1 in cervical carcinoma and choriocarcinoma cells
Ronald T. K. Pang et al.
CARCINOGENESIS (2010)
miR-130b Promotes CD133+ Liver Tumor-Initiating Cell Growth and Self-Renewal via Tumor Protein 53-Induced Nuclear Protein 1
Stephanie Ma et al.
CELL STEM CELL (2010)
Oxygen in Stem Cell Biology: A Critical Component of the Stem Cell Niche
Ahmed Mohyeldin et al.
CELL STEM CELL (2010)
miR-21 and miR-31 Converge on TIAM1 to Regulate Migration and Invasion of Colon Carcinoma Cells
Charisa L. Cottonham et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
The miR-17-92 MicroRNA Cluster Regulates Multiple Components of the TGF-β Pathway in Neuroblastoma
Pieter Mestdagh et al.
MOLECULAR CELL (2010)
Loss of miR-200 Inhibition of Suz12 Leads to Polycomb-Mediated Repression Required for the Formation and Maintenance of Cancer Stem Cells
Dimitrios Iliopoulos et al.
MOLECULAR CELL (2010)
Chromatin remodelling during development
Lena Ho et al.
NATURE (2010)
Histone deacetylase and Cullin3-RENKCTD11 ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation
Gianluca Canettieri et al.
NATURE CELL BIOLOGY (2010)
Wnt activity defines colon cancer stem cells and is regulated by the microenvironment
Louis Vermeulen et al.
NATURE CELL BIOLOGY (2010)
Loss of the tumor suppressor Snf5 leads to aberrant activation of the Hedgehog-Gli pathway
Zainab Jagani et al.
NATURE MEDICINE (2010)
miR-380-5p represses p53 to control cellular survival and is associated with poor outcome in MYCN-amplified neuroblastoma
Alexander Swarbrick et al.
NATURE MEDICINE (2010)
MicroRNA control of signal transduction
Masafumi Inui et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
GAM/ZFp/ZNF512B is central to a gene sensor circuitry involving cell-cycle regulators, TGFβ effectors, Drosha and microRNAs with opposite oncogenic potentials
Esmerina Tili et al.
NUCLEIC ACIDS RESEARCH (2010)
Transcriptional properties of human NANOG1 and NANOG2 in acute leukemic cells
Irina Eberle et al.
NUCLEIC ACIDS RESEARCH (2010)
TGFβ-mediated upregulation of hepatic miR-181b promotes hepatocarcinogenesis by targeting TIMP3
B. Wang et al.
ONCOGENE (2010)
De-repression of CTGF via the miR-17-92 cluster upon differentiation of human glioblastoma spheroid cultures
A. Ernst et al.
ONCOGENE (2010)
AP-1-Dependent miR-21 Expression Contributes to Chemoresistance in Cancer Stem Cell-Like SP Cells
Aya Misawa et al.
ONCOLOGY RESEARCH (2010)
Identification of MicroRNA-21 as a Biomarker for Chemoresistance and Clinical Outcome Following Adjuvant Therapy in Resectable Pancreatic Cancer
Jin-Hyeok Hwang et al.
PLOS ONE (2010)
Epithelial to Mesenchymal Transition Is Mechanistically Linked with Stem Cell Signatures in Prostate Cancer Cells
Dejuan Kong et al.
PLOS ONE (2010)
Stem cell-like micro-RNA signature driven by Myc in aggressive liver cancer
Stefano Cairo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Frequent Mutations of Chromatin Remodeling Gene ARID1A in Ovarian Clear Cell Carcinoma
Sian Jones et al.
SCIENCE (2010)
Targeted Overexpression of EZH2 in the Mammary Gland Disrupts Ductal Morphogenesis and Causes Epithelial Hyperplasia
Xin Li et al.
AMERICAN JOURNAL OF PATHOLOGY (2009)
MicroRNA-122a functions as a novel tumor suppressor downstream of adenomatous polyposis coli in gastrointestinal cancers
Xian Wang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
Cyclic stretch induced miR-146a upregulation delays C2C12 myogenic differentiation through inhibition of Numb
Wei Kuang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
Embryonic stem cell markers expression in cancers
Matthieu Schoenhals et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
High miR-21 expression in breast cancer associated with poor disease-free survival in early stage disease and high TGF-β1
Biyun Qian et al.
BREAST CANCER RESEARCH AND TREATMENT (2009)
Malignant Astrocytomas Originate from Neural Stem/Progenitor Cells in a Somatic Tumor Suppressor Mouse Models
Sheila Alcantara Llaguno et al.
CANCER CELL (2009)
The miR-17/92 Polycistron Is Up-regulated in Sonic Hedgehog-Driven Medulloblastomas and Induced by N-myc in Sonic Hedgehog-Treated Cerebellar Neural Precursors
Paul A. Northcott et al.
CANCER RESEARCH (2009)
Up-regulation of miR-200 and let-7 by Natural Agents Leads to the Reversal of Epithelial-to-Mesenchymal Transition in Gemcitabine-Resistant Pancreatic Cancer Cells
Yiwei Li et al.
CANCER RESEARCH (2009)
Loss of the SMRT/NCoR2 Corepressor Correlates with JAG2 Overexpression in Multiple Myeloma
Pushpankur Ghoshal et al.
CANCER RESEARCH (2009)
EZH2 Is Essential for Glioblastoma Cancer Stem Cell Maintenance
Mario-Luca Suva et al.
CANCER RESEARCH (2009)
Tobacco Smoke Induces Polycomb-Mediated Repression of Dickkopf-1 in Lung Cancer Cells
Mustafa Hussain et al.
CANCER RESEARCH (2009)
Acquisition of Epithelial-Mesenchymal Transition Phenotype of Gemcitabine-Resistant Pancreatic Cancer Cells Is Linked with Activation of the Notch Signaling Pathway
Zhiwei Wang et al.
CANCER RESEARCH (2009)
Chemoresistant Colorectal Cancer Cells, the Cancer Stem Cell Phenotype, and Increased Sensitivity to Insulin-like Growth Factor-I Receptor Inhibition
Nikolaos A. Dallas et al.
CANCER RESEARCH (2009)
MicroRNA-34a Inhibits Glioblastoma Growth by Targeting Multiple Oncogenes
Yunqing Li et al.
CANCER RESEARCH (2009)
Epithelial to Mesenchymal Transition Contributes to Drug Resistance in Pancreatic Cancer
Thiruvengadam Arumugam et al.
CANCER RESEARCH (2009)
Downregulation of miRNA-200c Links Breast Cancer Stem Cells with Normal Stem Cells
Yohei Shimono et al.
CELL (2009)
Epigenetic maintenance of stemness and malignancy in peripheral neuroectodermal tumors by EZH2
Stefan Burdach et al.
CELL CYCLE (2009)
The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype
John M. Heddleston et al.
CELL CYCLE (2009)
BMP-6 inhibits microRNA-21 expression in breast cancer through repressing δEF1 and AP-1
Jun Du et al.
CELL RESEARCH (2009)
Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression
Don L. Gibbons et al.
GENES & DEVELOPMENT (2009)
Identification of MicroRNA-181 by Genome-Wide Screening as a Critical Player in EpCAM-Positive Hepatic Cancer Stem Cells
Junfang Ji et al.
HEPATOLOGY (2009)
Epigenetic regulation of microRNA expression in colorectal cancer
Eva Bandres et al.
INTERNATIONAL JOURNAL OF CANCER (2009)
The Neuronal MicroRNA miR-326 Acts in a Feedback Loop with Notch and Has Therapeutic Potential against Brain Tumors
Benjamin Kefas et al.
JOURNAL OF NEUROSCIENCE (2009)
BMI1 Sustains Human Glioblastoma Multiforme Stem Cell Renewal
Mohamed Abdouh et al.
JOURNAL OF NEUROSCIENCE (2009)
Downregulated MicroRNA-200a in Meningiomas Promotes Tumor Growth by Reducing E-Cadherin and Activating the Wnt/β-Catenin Signaling Pathway
Okay Saydam et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
MicroRNA-21 modulates biological functions of pancreatic cancer cells including their proliferation, invasion, and chemoresistance
Taiki Moriyama et al.
MOLECULAR CANCER THERAPEUTICS (2009)
The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs
Ulrich Wellner et al.
NATURE CELL BIOLOGY (2009)
Lin28 promotes transformation and is associated with advanced human malignancies
Srinivas R. Viswanathan et al.
NATURE GENETICS (2009)
Cancer stem cells: mirage or reality?
Piyush B. Gupta et al.
NATURE MEDICINE (2009)
MicroRNAs: key regulators of stem cells
Vamsi K. Gangaraju et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)
Epigenetic regulation of CD133 and tumorigenicity of CD133+ovarian cancer cells
T. Baba et al.
ONCOGENE (2009)
The SWI/SNF complex and cancer
D. Reisman et al.
ONCOGENE (2009)
Antisense Inhibition of microRNA-21 or-221 Arrests Cell Cycle, Induces Apoptosis, and Sensitizes the Effects of Gemcitabine in Pancreatic Adenocarcinoma
Jong-Kook Park et al.
PANCREAS (2009)
MicroRNA-199b-5p Impairs Cancer Stem Cells through Negative Regulation of HES1 in Medulloblastoma
Livia Garzia et al.
PLOS ONE (2009)
MicroRNA miR-34 Inhibits Human Pancreatic Cancer Tumor-Initiating Cells
Qing Ji et al.
PLOS ONE (2009)
The miR-17∼92 cluster collaborates with the Sonic Hedgehog pathway in medulloblastoma
Tamar Uziel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits
Kornelia Polyak et al.
NATURE REVIEWS CANCER (2009)
Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres
Qing Ji et al.
BMC CANCER (2008)
DACT3 is an epigenetic regulator of Wnt/β-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications
Xia Jiang et al.
CANCER CELL (2008)
Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells
Jeongwu Lee et al.
CANCER CELL (2008)
Abnormal DNA methylation of CD133 in colorectal and glioblastoma tumors
Joo Mi Yi et al.
CANCER RESEARCH (2008)
Epigenetic inactivation of the canonical Wnt antagonist SRY-Box containing gene 17 in colorectal cancer
Wei Zhang et al.
CANCER RESEARCH (2008)
Emerging Role of miR-106b-25/miR-17-92 Clusters in the Control of Transforming Growth Factor β Signaling
Fabio Petrocca et al.
CANCER RESEARCH (2008)
A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition
Cameron P. Bracken et al.
CANCER RESEARCH (2008)
Regulation of the adenomatous polyposis coli gene by the miR-135 family in colorectal cancer
Remco Nagel et al.
CANCER RESEARCH (2008)
The epithelial-mesenchymal transition generates cells with properties of stem cells
Sendurai A. Mani et al.
CELL (2008)
Module map of stem cell genes guides creation of epithelial cancer stem cells
David J. Wong et al.
CELL STEM CELL (2008)
The upstream components of the Wnt signalling pathway in the dynamic EMT and MET associated with colorectal cancer progression
Elizabeth Vincan et al.
CLINICAL & EXPERIMENTAL METASTASIS (2008)
Hedgehog Signaling in Development and Cancer
Jin Jiang et al.
DEVELOPMENTAL CELL (2008)
Epithelial-mesenchymal transition: At the crossroads of development and tumor metastasis
Jing Yang et al.
DEVELOPMENTAL CELL (2008)
Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells
Elisabetta Ferretti et al.
EMBO JOURNAL (2008)
A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells
Ulrike Burk et al.
EMBO REPORTS (2008)
Epigenetic gene silencing in the Wnt pathway in breast cancer
George J. Klarmann et al.
EPIGENETICS (2008)
The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
Sun-Mi Park et al.
GENES & DEVELOPMENT (2008)
BMP signaling in dermal papilla cells is required for their hair follicle-inductive properties
Michael Rendl et al.
GENES & DEVELOPMENT (2008)
Upregulation of miR-23a∼27a∼24 decreases transforming growth factor-beta-induced tumor-suppressive activities in human hepatocellular carcinoma cells
Shenglin Huang et al.
INTERNATIONAL JOURNAL OF CANCER (2008)
The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2
Manav Korpal et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
MicroRNA-155 Is Regulated by the Transforming Growth Factor β/Smad Pathway and Contributes to Epithelial Cell Plasticity by Targeting RhoA
William Kong et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Polycomb complex 2 is required for E-cadherin repression by the snail1 transcription factor
Nicolas Herranz et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Histone modifications at the ABCG2 promoter following treatment with histone deacetylase inhibitor mirror those in multidrug-resistant cells
Kenneth K. W. To et al.
MOLECULAR CANCER RESEARCH (2008)
Efficient tumour formation by single human melanoma cells
Elsa Quintana et al.
NATURE (2008)
Cyclic dermal BMP signalling regulates stem cell activation during hair regeneration
Maksim V. Plikus et al.
NATURE (2008)
The mir-200 family and mir-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
Philip A. Gregory et al.
NATURE CELL BIOLOGY (2008)
The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities
Desiree Bonci et al.
NATURE MEDICINE (2008)
Molecular origins of cancer: Epigenetics in cancer
Manel Esteller
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Repression of E-cadherin by the polycomb group protein EZH2 in cancer
Q. Cao et al.
ONCOGENE (2008)
Colorectal Cancer Stem Cells Are Enriched in Xenogeneic Tumors Following Chemotherapy
Scott J. Dylla et al.
PLOS ONE (2008)
Sustained induction of epithelial to mesenchymal transition activates DNA methylation of genes silenced in basal-like breast cancers
Nancy Dumont et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Cell type-specific DNA methylation patterns in the human breast
Noga Bloushtain-Qimron et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Identification of a novel putative gastrointestinal stem cell and adenoma stem cell marker, doublecortin and CaM kinase-like-1, following radiation injury and in adenomatous polyposis coli/multiple intestinal neoplasia mice
Randal May et al.
STEM CELLS (2008)
Pharmacological inhibition of DNA methylation induces proinvasive and prometastatic genes in vitro and in vivo
Shafaat A. Rabbani
NEOPLASIA (2008)
CD133+ HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB survival pathway
S. Ma et al.
ONCOGENE (2008)
Iet-7 regulates self renewal and tumorigenicity of breast cancer cells
Fengyan Yu et al.
CELL (2007)
Development and characterization of gemcitabine-resistant pancreatic tumor cells
Ami N. Shah et al.
ANNALS OF SURGICAL ONCOLOGY (2007)
MLL translocations, histone modifications and leukaemia stem-cell development
Andrei V. Krivtsov et al.
NATURE REVIEWS CANCER (2007)
Colon cancer stem cells dictate tumor growth and resist cell death by production of interleukin-4
Matilde Todaro et al.
CELL STEM CELL (2007)
Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer
Patrick C. Hermann et al.
CELL STEM CELL (2007)
p53-mediated activation of miRNA34 candidate tumor-suppressor genes
Guido T. Bommer et al.
CURRENT BIOLOGY (2007)
Differential regulation of microRNAs by p53 revealed by massively parallel Sequencing -: miR-34a is a p53 target that induces apoptosis and G1-arrest
Valery Tarasov et al.
CELL CYCLE (2007)
A microRNA component of the p53 tumour suppressor network
Lin He et al.
NATURE (2007)
Bmi-1 is a target gene for SALL4 in hematopoietic and leukemic cells
Jianchang Yang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis
Tsung-Cheng Chang et al.
MOLECULAR CELL (2007)
Transcriptional activation of miR-34a contributes to p53-mediated apoptosis
Nina Raver-Shapira et al.
MOLECULAR CELL (2007)
Wnt/β-catenin signaling in cancer stemness and malignant behavior
Riccardo Fodde et al.
CURRENT OPINION IN CELL BIOLOGY (2007)
Genetic unmasking of an epigenetically silenced microRNA in human cancer cells
Amaia Lujambio et al.
CANCER RESEARCH (2007)
Epigenetic stem cell signature in cancer
Martin Widschwendter et al.
NATURE GENETICS (2007)
Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer
Yeshayahu Schlesinger et al.
NATURE GENETICS (2007)
A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing
Joyce E. Ohm et al.
NATURE GENETICS (2007)
Histone arginine methylation regulates pluripotency in the early mouse embryo
Maria-Elena Torres-Padilla et al.
NATURE (2007)
A perivascular niche for brain tumor stem cells
Christopher Calabrese et al.
CANCER CELL (2007)
Wnt signalingg stem cells and the cellular origin of breast cancer
Charlotta Lindvall et al.
STEM CELL REVIEWS (2007)
Networking of WNT, FGF, notch, BMP, and hedgehog signaling pathways during carcinogenesis
Masaru Katoh
STEM CELL REVIEWS (2007)
The role of epithelial-mesenchymal transition in cancer pathology
Marcello Guarino et al.
PATHOLOGY (2007)
Histone acetyltransferase complexes: one size doesn't fit all
Kenneth K. Lee et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Mining the Wnt pathway for cancer therapeutics
Nick Barker et al.
NATURE REVIEWS DRUG DISCOVERY (2006)
Wnt/β-catenin signaling in development and disease
Hans Clevers
CELL (2006)
Circular chromosome conformation capture (4C) uncovers extensive networks of epigenetically regulated intra- and interchromosomal interactions
Zhihu Zhao et al.
NATURE GENETICS (2006)
Polycomb silencers control cell fate, development and cancer
Anke Sparmann et al.
NATURE REVIEWS CANCER (2006)
Orchestrating ontogenesis: variations on a theme by sonic hedgehog
Philip W. Ingham et al.
NATURE REVIEWS GENETICS (2006)
Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia
Tim C. P. Somervaille et al.
CANCER CELL (2006)
Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9
Andrei V. Krivtsov et al.
NATURE (2006)
c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma
Andrew P. Weng et al.
GENES & DEVELOPMENT (2006)
Chemotherapy resistance of glioblastoma stem cells
A. Eramo et al.
CELL DEATH AND DIFFERENTIATION (2006)
Cyclooxygenase-2-dependent regulation of E-cadherin:: Prostaglandin E2 induces transcriptional repressors ZEB1 and snail in non-small cell lung cancer
Mariam Dohadwala et al.
CANCER RESEARCH (2006)
Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions
AP Bracken et al.
GENES & DEVELOPMENT (2006)
Control of developmental regulator's by polycomb in human embryonic stem cells
TI Lee et al.
CELL (2006)
Oncomirs - microRNAs with a role in cancer
A Esquela-Kerscher et al.
NATURE REVIEWS CANCER (2006)
E-cadherin transcriptional downregulation by promoter methylation but not mutation is related to epithelial-to-mesenchymal transition in breast cancer cell lines
M Lombaerts et al.
BRITISH JOURNAL OF CANCER (2006)
The Polycomb group protein EZH2 directly controls DNA methylation
E Viré et al.
NATURE (2006)
A microRNA expression signature of human solid tumors defines cancer gene targets
S Volinia et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Complex networks orchestrate epithelial-mesenchymal transitions
JP Thiery et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2006)
Aberrant activation of Notch signaling in human breast cancer
S Stylianou et al.
CANCER RESEARCH (2006)
Genomic DNA methylation: the mark and its mediators
RJ Klose et al.
TRENDS IN BIOCHEMICAL SCIENCES (2006)
NOTCH signaling as a novel cancer therapeutic target
L. Miele et al.
CURRENT CANCER DRUG TARGETS (2006)
The epigenetic progenitor origin of human cancer
AP Feinberg et al.
NATURE REVIEWS GENETICS (2006)
Global loss of imprinting leads to widespread tumorigenesis in adult mice
TM Holm et al.
CANCER CELL (2005)
Global histone modification patterns predict risk of prostate cancer recurrence
DB Seligson et al.
NATURE (2005)
Increased expression of historic deacetylase 2 is found in human gastric cancer
J Song et al.
APMIS (2005)
Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer
MF Fraga et al.
NATURE GENETICS (2005)
DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells
A Eger et al.
ONCOGENE (2005)
Discovery of aberrant expression of R-RAS by cancer-linked DNA hypomethylation in gastric cancer using microarrays
M Nishigaki et al.
CANCER RESEARCH (2005)
RAS is regulated by the let-7 MicroRNA family
SM Johnson et al.
CELL (2005)
Upregulation and nuclear recruitment of HDACI in hormone refractory prostate cancer
K Halkidou et al.
PROSTATE (2004)
Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer
H Suzuki et al.
NATURE GENETICS (2004)
The diverse superfamily of lysine acetyltransferases and their roles in leukemia and other diseases
XJ Yang
NUCLEIC ACIDS RESEARCH (2004)
The SWI/SNF complex - Chromatin and cancer
CWM Roberts et al.
NATURE REVIEWS CANCER (2004)
Cancer genes and the pathways they control
B Vogelstein et al.
NATURE MEDICINE (2004)
Silencing of human polycomb target genes is associated with methylation of histone H3 Lys 27
A Kirmizis et al.
GENES & DEVELOPMENT (2004)
Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis
J Yang et al.
CELL (2004)
Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complex
H Peinado et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Epigenetic regulation of cellular memory by the polycomb and trithorax group proteins
L Ringrose et al.
ANNUAL REVIEW OF GENETICS (2004)
Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis
S Pece et al.
JOURNAL OF CELL BIOLOGY (2004)
Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors
A Cozzio et al.
GENES & DEVELOPMENT (2003)
Hedgehog signalling in cancer formation and maintenance
MP di Magliano et al.
NATURE REVIEWS CANCER (2003)
Cell-type-specific repression of the maspin gene is disrupted frequently by demethylation at the promoter region in gastric intestinal metaplasia and cancer cells
Y Akiyama et al.
AMERICAN JOURNAL OF PATHOLOGY (2003)
Gene repression by Polycomb group protein complexes: a distinct complex for every occasion?
AP Otte et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2003)
Chromosomal instability and tumors promoted by DNA hypomethylation
A Eden et al.
SCIENCE (2003)
Loss of IGF2 imprinting:: A potential marker of colorectal cancer risk
HM Cui et al.
SCIENCE (2003)
Epithelial-mesenchymal transitions:: A mesodermal cell strategy for evolutive innovation in Metazoans
JM Pérez-Pomares et al.
ANATOMICAL RECORD (2002)
Heterogeneity in the modification and involvement of chromatin components of the CpG island of the silenced human CDH1 gene in cancer cells
S Koizume et al.
NUCLEIC ACIDS RESEARCH (2002)
Regulation of DNA methylation in human breast cancer - Effect on the urokinase-type plasminogen activator gene production and tumor invasion
YJ Guo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Active genes are tri-methylated at K4 of histone H3
H Santos-Rosa et al.
NATURE (2002)
Decreased efficiency of γ-ray-induced DNA double-strand break rejoining in malignant transformants of human bronchial epithelial cells generated by alpha-particle exposure
JF Sun et al.
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY (2002)
Methylation of histone H3 Lys 4 in coding regions of active genes
BE Bernstein et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
DNA methylation patterns and epigenetic memory
A Bird
GENES & DEVELOPMENT (2002)
The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion
J Comijn et al.
MOLECULAR CELL (2001)
The transcription factor Snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression
A Cano et al.
NATURE CELL BIOLOGY (2000)
分享论文
