期刊
MOLECULAR NUTRITION & FOOD RESEARCH
卷 57, 期 1, 页码 58-70出版社
WILEY
DOI: 10.1002/mnfr.201200454
关键词
Cardiovascular; Insulin; Lipid metabolism; MicroRNA; Polyphenols
资金
- Spanish Government [AGL 2008-00387/ALI]
MicroRNAs (miRNAs) are small noncoding RNAs, approximately 1825 nucleotides in length, that modulate gene expression at the posttranscriptional level. Thousands of miRNAs have been described, and it is thought that they regulate some aspects of more than 60% of all human cell transcripts. Several polyphenols have been shown to modulate miRNAs related to metabolic homeostasis and chronic diseases. Polyphenolic modulation of miRNAs is very attractive as a strategy to target numerous cell processes and potentially reduce the risk of chronic disease. Evidence is building that polyphenols can target specific miRNAs, such as miR-122, but more studies are necessary to discover and validate additional miRNA targets.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据