期刊
MOLECULAR MICROBIOLOGY
卷 81, 期 3, 页码 581-587出版社
WILEY-BLACKWELL
DOI: 10.1111/j.1365-2958.2011.07747.x
关键词
-
资金
- Fonds der Chemischen Industrie
- Deutsche Forschungsgemeinschaft [MA2837/1-3]
Investigations into the resistance mechanisms of Firmicutes bacteria against antimicrobial peptides have revealed unique resistance modules comprised of an unusual type of ATP-binding cassette (ABC) transporter, paired with a two-component regulatory system. In these systems, the ABC-transporter is not only involved in detoxification of the peptides, but also in their detection and resulting regulation of gene expression. The manuscript by Hiron et al. (2011) published in this issue describes an intriguing complexity of regulatory circuits and division of labour between the three paralogous modules in Staphylococcus aureus, providing important mechanistic insights and new perspectives for future investigations of these unique systems.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据