期刊
MOLECULAR MEMBRANE BIOLOGY
卷 26, 期 1-2, 页码 67-79出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/09687680802620351
关键词
Palmitoylation; protein sorting; membrane microdomains; lipid rafts; protein trafficking
资金
- Medical Research Council
- Wellcome Trust
- Medical Research Council [G0601597] Funding Source: researchfish
- MRC [G0601597] Funding Source: UKRI
The attachment of palmitic acid to the amino acid cysteine via thioester linkage (S-palmitoylation) is a common post-translational modification of eukaryotic proteins. In this review, we discuss the role of palmitoylation as a versatile protein sorting signal, regulating protein trafficking between distinct intracellular compartments and the micro-localization of proteins within membranes.
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