期刊
MOLECULAR MEMBRANE BIOLOGY
卷 25, 期 4, 页码 321-U15出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/09687680802050385
关键词
P2X purinergic receptors; assembly; trafficking
资金
- Biotechnology and Biological Sciences Research Council [BB/F001320/1] Funding Source: Medline
- BBSRC [BB/F001320/1] Funding Source: UKRI
P2X receptors are cation selective ion channels gated by the binding of extracellular ATP. Seven subtypes have been identified and they have widespread and overlapping distributions throughout the body. They form homo- and heterotrimeric complexes that differ in their functional properties and subcellular localization. They form part of larger signalling complexes, interacting with unrelated ion channels and other membrane and cytosolic proteins. Up- or down-regulation of their expression is associated with several disease states. This review aims to summarize recent work on the assembly and trafficking of this family of receptors.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据