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Daniel T. Starczynowski et al.
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Sonja J. Heidorn et al.
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Vincent F. Taelman et al.
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RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF
Poulikos I. Poulikakos et al.
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Georgia Hatzivassiliou et al.
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[Anonymous]
CELL (2009)
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Nicola Normanno et al.
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Etienne Meylan et al.
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The signaling adaptor p62 is an important NF-κB mediator in tumorigenesis
Angeles Duran et al.
CANCER CELL (2008)
Elevated CRAF as a potential mechanism of acquired resistance to BRAF inhibition in melanoma
Clara Montagut et al.
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K-ras mutations and benefit from cetuximab in advanced colorectal cancer
Christos S. Karapetis et al.
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Aberrant cytoplasmic localization of N-CoR in colorectal tumors
Vanessa Fernandez-Majada et al.
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Jun-Li Luo et al.
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Shashi Prajapati et al.
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JE Hoberg et al.
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A nucleosomal function for IκB kinase-α in NF-κB-dependent gene expression
V Anest et al.
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Histone H3 phosphorylation by IKK-α is critical for cytokine-induced gene expression
Y Yamamoto et al.
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Activation by IKKα of a second, evolutionary conserved, NF-κB signaling pathway
U Senftleben et al.
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Annexin VI stimulates endocytosis and is involved in the trafficking of low density lipoprotein to the prelysosomal compartment
T Grewal et al.
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The atypical PKC-interacting protein p62 channels NF-κB activation by the IL-1-TRAF6 pathway
L Sanz et al.
EMBO JOURNAL (2000)
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