Amyloid A beta cut from APP by beta-secretase BACE1 and gamma-secretase, induces apoptosis via opening type-1 porin/VDAC in cell membranes of hypometabolic cells-A basic model for the induction of apoptosis!?

MOLECULAR GENETICS AND METABOLISM

卷 101, 期 2-3, 页码 301-303

ACADEMIC PRESS INC ELSEVIER SCIENCE

Apoptosis induction; Extrinsic pathway; Amyloid A beta; VDAC; Porin; Plasma lemma; Channel opening; Alzheimer; Down syndrome; Amyotrophic lateral sclerosis; ALS

Endocrinology & Metabolism Genetics & Heredity Medicine, Research & Experimental