期刊
MOLECULAR ECOLOGY RESOURCES
卷 10, 期 6, 页码 986-994出版社
WILEY-BLACKWELL
DOI: 10.1111/j.1755-0998.2010.02840.x
关键词
co-ancestry; genotypes; marker; natural populations; relatedness
Molecular marker data provide a means of circumventing the problem of not knowing the population structure of a natural population, as observed similarities between a pair's genotypes provide information on their genetic relationship. Numerous method-of-moment (MOM) estimators have been developed for estimating relationship coefficients using this information. Here, I present a simplified form of Wang's 2002 relationship estimator that is not dependent upon a previously required weighting scheme, thus improving the efficiency of the estimator when used with genuinely related pairs. The new estimator is compared against other estimators under a range of conditions, including situations where the parameter estimates are truncated to lie within the legitimate parameter space. The advantages of the new estimator are most notable for the two-gene coefficient of relatedness. Truncating the MOM estimators results in parameter estimates whose properties are similar to maximum likelihood estimates, with them having generally lower sampling variances, but being biased.
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