期刊
MOLECULAR DIVERSITY
卷 23, 期 1, 页码 215-259出版社
SPRINGER
DOI: 10.1007/s11030-018-9870-z
关键词
Chan-Lam coupling; Cross-coupling reactions; Boronic acids; N-heterocycles; N-Arylation
Chan-Lam coupling is one of the most popular and easy methods to perform arylation of amines (N-arylations). This cross-coupling is generally performed by reacting aryl boronate derivatives with a variety of substrates involving nitrogen containing functional groups such as amines, amides, ureas, hydrazine, carbamates. This article summarizes the synthetic applications of this reaction and the efforts of scientists to develop novel and efficient methodologies for this reaction.
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