期刊
MOLECULAR DIVERSITY
卷 15, 期 2, 页码 497-505出版社
SPRINGER
DOI: 10.1007/s11030-010-9272-3
关键词
Pyrazolo[4,3-f]quinoline derivatives; Diversity-oriented synthesis; Multi-component reactions; Microwave irradiation; MW; DOS; MCR
类别
资金
- National Science Foundation of China [21072163, 21002083]
- Science Foundation in Interdisciplinary Major Research Project of Xuzhou Normal University [09XKXK01]
- Science & Technology Foundation of Xuzhou municipal government [XM08C027]
- Natural Science Foundation [09KJB150011]
- Jiangsu high education committee [08QLT001]
Six new series of pyrazolo[4,3-f]quinoline derivatives with potential bioactivities were synthesized by the three-component reactions of aromatic aldehydes, 5-aminoindazole, and various cyclic 1,3-dicarbonyl compounds under microwave irradiation. This protocol has the valuable features of structural diversity of products, broader substrate scope, operational simplicity, high yields, and short reaction time. Moreover, the structure of compound 88a was confirmed by an X-ray crystallographic analysis and attested to the chemoselectivity of reaction where 1-methyl barbituric acid participated.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据