期刊
MOLECULAR CELL
卷 54, 期 2, 页码 309-320出版社
CELL PRESS
DOI: 10.1016/j.molcel.2014.03.039
关键词
-
资金
- Canadian Institutes of Health Research (CIHR)
- Canadian Cancer Society (CCS)
- Becas Chile
In recent years, our understanding of the mechanisms underlying colorectal carcinogenesis has vastly expanded. Underlying inflammation within the intestine, diet, and most recently, the gut microbiota, have been demonstrated to influence the development of colorectal cancer. However, since cancer is ultimately a genetic disease, these factors are thought to create genotoxic stress within the intestinal environment to promote genetic and epigenetic alterations leading to cancer. In this review, we will focus on how gut microbes intersect with inflammation, diet, and host genetics to influence the development of colon cancer.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据