4.7 Article

Small molecule kinase inhibitor LRRK2-IN-1 demonstrates potent activity against colorectal and pancreatic cancer through inhibition of doublecortin-like kinase 1

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Genetics & Heredity

Dclk1 distinguishes between tumor and normal stem cells in the intestine

Yuki Nakanishi et al.

NATURE GENETICS (2013)

Article Multidisciplinary Sciences

Bmi1 Enhances Tumorigenicity and Cancer Stem Cell Function in Pancreatic Adenocarcinoma

Erica Proctor et al.

PLOS ONE (2013)

Article Gastroenterology & Hepatology

Activation of two distinct Sox9-EGFP-expressing intestinal stem cell populations during crypt regeneration after irradiation

Laurianne Van Landeghem et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2012)

Article Biochemistry & Molecular Biology

Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism

Haoqiang Ying et al.

Article Biochemistry & Molecular Biology

EMT and Dissemination Precede Pancreatic Tumor Formation

Andrew D. Rhim et al.

Review Biochemistry & Molecular Biology

The many faces and functions of β-catenin

Tomas Valenta et al.

EMBO JOURNAL (2012)

Article Cell Biology

Latent process genes for cell differentiation are common decoders of neurite extension length

Kanako Watanabe et al.

JOURNAL OF CELL SCIENCE (2012)

Article Oncology

Honokiol in Combination with Radiation Targets Notch Signaling to Inhibit Colon Cancer Stem Cells

Sivapriya Ponnurangam et al.

MOLECULAR CANCER THERAPEUTICS (2012)

Article Multidisciplinary Sciences

Progressive degeneration of human neural stem cells caused by pathogenic LRRK2

Guang-Hui Liu et al.

NATURE (2012)

Article Multidisciplinary Sciences

Comprehensive molecular characterization of human colon and rectal cancer

Donna M. Muzny et al.

NATURE (2012)

Article Biochemistry & Molecular Biology

Using transcriptome sequencing to identify mechanisms of drug action and resistance

Sarah A. Wacker et al.

NATURE CHEMICAL BIOLOGY (2012)

Article Multidisciplinary Sciences

Lineage Tracing Reveals Lgr5+ Stem Cell Activity in Mouse Intestinal Adenomas

Arnout G. Schepers et al.

SCIENCE (2012)

Article Biochemistry & Molecular Biology

Influence of Ser/Pro-rich domain and kinase domain of double cortin-like protein kinase on microtubule-binding activity

Tadashi Nagamine et al.

JOURNAL OF BIOCHEMISTRY (2011)

Article Chemistry, Medicinal

LigPlot+: Multiple Ligand-Protein Interaction Diagrams for Drug Discovery

Roman A. Laskowski et al.

JOURNAL OF CHEMICAL INFORMATION AND MODELING (2011)

Article Oncology

Multicenter Independent Assessment of Outcomes in Chronic Myeloid Leukemia Patients Treated With Imatinib

Carlo Gambacorti-Passerini et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2011)

Article Biotechnology & Applied Microbiology

Comprehensive analysis of kinase inhibitor selectivity

Mindy I. Davis et al.

NATURE BIOTECHNOLOGY (2011)

Article Biochemistry & Molecular Biology

Characterization of a selective inhibitor of the Parkinson's disease kinase LRRK2

Xianming Deng et al.

NATURE CHEMICAL BIOLOGY (2011)

Article Multidisciplinary Sciences

β-catenin/TCF4 complex induces the epithelial-to-mesenchymal transition (EMT)-activator ZEB1 to regulate tumor invasiveness

Ester Sanchez-Tillo et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Review Multidisciplinary Sciences

A Perspective on Cancer Cell Metastasis

Christine L. Chaffer et al.

SCIENCE (2011)

Article Gastroenterology & Hepatology

Identification of a novel putative pancreatic stem/progenitor cell marker DCAMKL-1 in normal mouse pancreas

Randal May et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2010)

Article Gastroenterology & Hepatology

Selective Blockade of DCAMKL-1 Results in Tumor Growth Arrest by a Let-7a MicroRNA-Dependent Mechanism

Sripathi M. Sureban et al.

GASTROENTEROLOGY (2009)

Article Medicine, General & Internal

Gefitinib or Carboplatin-Paclitaxel in Pulmonary Adenocarcinoma.

Tony S. Mok et al.

NEW ENGLAND JOURNAL OF MEDICINE (2009)

Review Oncology

Targeting cancer with small molecule kinase inhibitors

Jianming Zhang et al.

NATURE REVIEWS CANCER (2009)

Article Medicine, General & Internal

Sorafenib in advanced hepatocellular carcinoma

Josep M. Llovet et al.

NEW ENGLAND JOURNAL OF MEDICINE (2008)

Article Biochemistry & Molecular Biology

Expression, characterization, and gene knockdown of zebrafish doublecortin-like protein kinase

Sachiko Shimomura et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2007)

Review Biochemistry & Molecular Biology

MAP kinase signalling pathways in cancer

A. S. Dhillon et al.

ONCOGENE (2007)

Review Biochemistry & Molecular Biology

MAPK signalling: ERK5 versus ERK1/2

Satoko Nishimoto et al.

EMBO REPORTS (2006)

Article Chemistry, Multidisciplinary

UCSF chimera - A visualization system for exploratory research and analysis

EF Pettersen et al.

JOURNAL OF COMPUTATIONAL CHEMISTRY (2004)

Article Biochemistry & Molecular Biology

SWISS-MODEL: an automated protein homology-modeling server

T Schwede et al.

NUCLEIC ACIDS RESEARCH (2003)

Article Biochemistry & Molecular Biology

Taking geometry to its edge: Fast unbound rigid (and hinge-bent) docking

D Schneidman-Duhovny et al.

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2003)

Article Multidisciplinary Sciences

Origin of multidrug resistance in cells with and without multidrug resistance genes: Chromosome reassortments catalyzed by aneuploidy

P Duesberg et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Article Genetics & Heredity

Systematic variation in gene expression patterns in human cancer cell lines

DT Ross et al.

NATURE GENETICS (2000)