相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Mammalian Target of Rapamycin: Its Role in Early Neural Development and in Adult and Aged Brain Function
Carla Garza-Lombo et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2016)
ERK1/2 Phosphorylate Raptor to Promote Ras-dependent Activation of mTOR Complex 1 (mTORC1)
Audrey Carriere et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Odefy - From discrete to continuous models
Jan Krumsiek et al.
BMC BIOINFORMATICS (2010)
Requirement for nuclear factor kappa B signalling in the interleukin-1-induced expression of the CCAAT/enhancer binding protein-delta gene in hepatocytes
Saira Ali et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2010)
Computing Combinatorial Intervention Strategies and Failure Modes in Signaling Networks
Regina Samaga et al.
JOURNAL OF COMPUTATIONAL BIOLOGY (2010)
Networks Inferred from Biochemical Data Reveal Profound Differences in Toll-like Receptor and Inflammatory Signaling between Normal and Transformed Hepatocytes
Leonidas G. Alexopoulos et al.
MOLECULAR & CELLULAR PROTEOMICS (2010)
Rictor is a novel target of p70 S6 kinase-1
C. Treins et al.
ONCOGENE (2010)
Interleukin-1 (IL-1) Pathway
Axel Weber et al.
SCIENCE SIGNALING (2010)
PROMOT: modular modeling for systems biology
Sebastian Mirschel et al.
BIOINFORMATICS (2009)
Computing paths and cycles in biological interaction graphs
Steffen Klamt et al.
BMC BIOINFORMATICS (2009)
Transforming Boolean models to continuous models: methodology and application to T-cell receptor signaling
Dominik M. Wittmann et al.
BMC SYSTEMS BIOLOGY (2009)
HSP27 regulates IL-1 stimulated IKK activation through interacting with TRAF6 and affecting its ubiquitination
Yifan Wu et al.
CELLULAR SIGNALLING (2009)
Cellular mechanisms of insulin resistance: role of stress-regulated serine kinases and insulin receptor substrates (IRS) serine phosphorylation
Jean-Francois Tanti et al.
CURRENT OPINION IN PHARMACOLOGY (2009)
A new mechanism for the regulation of Gab1 recruitment to the plasma membrane
Rene Eulenfeld et al.
JOURNAL OF CELL SCIENCE (2009)
Characterization of Rictor Phosphorylation Sites Reveals Direct Regulation of mTOR Complex 2 by S6K1
Christian C. Dibble et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Discrete logic modelling as a means to link protein signalling networks with functional analysis of mammalian signal transduction
Julio Saez-Rodriguez et al.
MOLECULAR SYSTEMS BIOLOGY (2009)
The Logic of EGFR/ErbB Signaling: Theoretical Properties and Analysis of High-Throughput Data
Regina Samaga et al.
PLOS COMPUTATIONAL BIOLOGY (2009)
Flexible informatics for linking experimental data to mathematical models via DataRail
Julio Saez-Rodriguez et al.
BIOINFORMATICS (2008)
Oncogenic MAPK signaling stimulates mTORC1 activity by promoting RSK-mediated Raptor phosphorylation
Audrey Carriere et al.
CURRENT BIOLOGY (2008)
Multistability of signal transduction motifs
J. Saez-Rodriguez et al.
IET SYSTEMS BIOLOGY (2008)
c-Jun controls histone modifications, NF-κB recruitment, and RNA polymerase II function to activate the ccl2 gene
Sabine Wolter et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Regulation of interleukin-6-induced hepatic insulin resistance by mammalian target of rapamycin through the STAT3-SOCS3 pathway
Jeong-Ho Kim et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
The functional role of an interleukin 6-inducible CDK9•STAT3 complex in human γ-fibrinogen gene expression
Tieying Hou et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Activation of NF-κB by IL-1β blocks IL-6-induced sustained STAT3 activation and STAT3-dependent gene expression of the human γ-fibrinogen gene
Ute Albrecht et al.
CELLULAR SIGNALLING (2007)
A logical model provides insights into T cell receptor signaling
Julio Saez-Rodriguez et al.
PLOS COMPUTATIONAL BIOLOGY (2007)
Dynamical roles of biological regulatory circuits
Denis Thieffry
BRIEFINGS IN BIOINFORMATICS (2007)
Interleukin-1 (IL-1)-induced TAK1-dependent versus MEKK3-dependent NFκB activation pathways bifurcate at IL-1 receptor-associated kinase modification
Jianhong Yao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Interleukin-6 impairs the insulin signaling pathway, promoting production of nitric oxide in human umbilical vein endothelial cells
Francesco Andreozzi et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Structural and functional analysis of cellular networks with CellNetAnalyzer
Steffen Klamt et al.
BMC SYSTEMS BIOLOGY (2007)
Deactivation of Akt and STAT3 signaling promotes apoptosis, inhibits proliferation, and enhances the sensitivity of hepatocellular carcinoma cells to an anticancer agent, atiprimod
Sweeta R. Choudhari et al.
MOLECULAR CANCER THERAPEUTICS (2007)
Visual setup of logical models of signaling and regulatory networks with ProMoT
Julio Saez-Rodriguez et al.
BMC BIOINFORMATICS (2006)
A methodology for the structural and functional analysis of signaling and regulatory networks
S Klamt et al.
BMC BIOINFORMATICS (2006)
Essential role of STAT3 in cytokine-driven NF-κB-mediated serum amyloid A gene expression
K Hagihara et al.
GENES TO CELLS (2005)
Erk associates with and primes GSK-3β for its inactivation resulting in upregulation of β-catenin
QQ Ding et al.
MOLECULAR CELL (2005)
MEK1-dependent delayed expression of Fos-related antigen-1 counteracts c-Fos and p65 NF-κB-mediated interleukin-8 transcription in response to cytokines or growth factors
E Hoffmann et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB
DS Cai et al.
NATURE MEDICINE (2005)
Met, metastasis, motility and more
C Birchmeier et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2003)
Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes
JJ Senn et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Signal pathways involved in activation of p70S6K and phosphorylation of 4E-BP1 following exposure of multiple myeloma tumor cells to interleukin-6
YY Shi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Scatter-factor and semaphorin receptors: Cell signalling for invasive growth
L Trusolino et al.
NATURE REVIEWS CANCER (2002)
Multistationarity, the basis of cell differentiation and memory. I. Structural conditions of multistationarity and other nontrivial behavior
R Thomas et al.
CHAOS (2001)
Multistationarity, the basis of cell differentiation and memory. II. Logical analysis of regulatory networks in terms of feedback circuits
R Thomas et al.
CHAOS (2001)