期刊
MOLECULAR BIOSYSTEMS
卷 6, 期 3, 页码 481-493出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/b919670f
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资金
- NIH [R01GM52581, 5 T32 HD07149-32]
- Yale Liver Center [NIDDK P30-34989]
- Anna Fuller Fund Fellowship in Molecular Oncology
- EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT [T32HD007149] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R29GM052581, R01GM052581] Funding Source: NIH RePORTER
Ribosomes are vital for cell growth and survival. Until recently, it was believed that mutations in ribosomes or ribosome biogenesis factors would be lethal, due to the essential nature of these complexes. However, in the last few decades, a number of diseases of ribosome biogenesis have been discovered. It remains a challenge in the field to elucidate the molecular mechanisms underlying them.
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