期刊
MOLECULAR BIOSYSTEMS
卷 6, 期 9, 页码 1557-1560出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c002246b
关键词
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资金
- Office of Naval Research [N000140810738]
- Stony Brook University
Cyclic-di-GMP signaling is used by many bacteria to control biofilm formation. As biofilm formation is an important survival strategy for many bacteria, the synthesis and degradation of cyclic-di-GMP is tightly regulated by enzymes containing domains with conserved GGDEF and EAL sequence motifs, respectively. In this report we characterize a protein with both cyclase and phosphodiesterase activities and demonstrate that it contributes to secretion of the extracellular polysaccharide matrix, an important step in early biofilm formation.
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