期刊
SCIENCE
卷 347, 期 6220, 页码 436-438出版社
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.1261121
关键词
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资金
- Swedish Research Council
- Higher Education Commission of Pakistan
- CAnMove - Swedish Research Council
- CAnMove - Lund University
Recovery from infection is not always complete, and mild chronic infection may persist. Although the direct costs of such infections are apparently small, the potential for any long-term effects on Darwinian fitness is poorly understood. In a wild population of great reed warblers, we found that low-level chronic malaria infection reduced life span as well as the lifetime number and quality of offspring. These delayed fitness effects of malaria appear to be mediated by telomere degradation, a result supported by controlled infection experiments on birds in captivity. The results of this study imply that chronic infection may be causing a series of small adverse effects that accumulate and eventually impair phenotypic quality and Darwinian fitness.
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