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Takayuki Iriyama et al.
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The thioredoxin system: a key target in tumour and endothelial cells
A. Mukherjee et al.
BRITISH JOURNAL OF RADIOLOGY (2008)
Requirement of reactive oxygen species-dependent activation of ASK1-p38 MAPK pathway for extracellular ATP-induced apoptosis in macrophage
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Thioredoxin and TRAF family proteins regulate reactive oxygen species-dependent activation of ASK1 through reciprocal modulation of the N-terminal homophilic interaction of ASK1
Go Fujino et al.
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Disulfide bond-mediated multimerization of ask1 and its reduction by thioredoxin-1 regulate H2O2-induced c-jun NH2-terminal kinase activation and apoptosis
Philippe J. Nadeau et al.
MOLECULAR BIOLOGY OF THE CELL (2007)
ROS as signalling molecules:: mechanisms that generate specificity in ROS homeostasis
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Selective redox regulation of cytokine receptor signaling by extracellular thioredoxin-1
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Hydrogen peroxide: A signaling messenger
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ANTIOXIDANTS & REDOX SIGNALING (2006)
Thioredoxin-1 and posttranslational modifications
Judith Haendeler
ANTIOXIDANTS & REDOX SIGNALING (2006)
Recruitment of tumor necrosis factor receptor-associated factor family proteins to apoptosis signal-regulating kinase 1 signalosome is essential for oxidative stress-induced cell death
T Noguchi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Apoptosis signal-regulating kinase 1 is involved not only in apoptosis but also in non-apoptotic cardiomyocyte death
T Watanabe et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Protein kinase D specifically mediates apoptosis signal-regulating kinase 1-JNK signaling induced by H2O2 but not tumor necrosis factor
W Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Amyloid beta induces neuronal cell death through ROS-mediated ASK1 activation
H Kadowaki et al.
CELL DEATH AND DIFFERENTIATION (2005)
Oxidant hypersensitivity of Fanconi anemia type C-deficient cells is dependent on a redox-regulated apoptotic pathway
MR Saadatzadeh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Activation of apoptosis signal-regulating kinase 1 by reactive oxygen species through dephosphorylation at serine 967 and 14-3-3 dissociation
EH Goldman et al.
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Inhibition of apoptosis signal-regulating kinase 1 by nitric oxide through a thiol redox mechanism
HS Park et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Thioredoxin-1 binds to the C2 domain of PTEN inhibiting PTEN's lipid phosphatase activity and membrane binding: a mechanism for the functional loss of PTEN's tumor suppressor activity
EJ Meuillet et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2004)
Oxidative stress inhibits MEKK1 by site-specific glutathionylation in the ATP-binding domain
JV Cross et al.
BIOCHEMICAL JOURNAL (2004)
Negative control of apoptosis signal-regulating kinase 1 through phosphorylation of Ser-1034
K Fujii et al.
ONCOGENE (2004)
Thioredoxin-2 inhibits mitochondria-located ASK1-mediated apoptosis in a JNK-independent manner
R Zhang et al.
CIRCULATION RESEARCH (2004)
AIP1/DAB2IP, a novel member of the Ras-GAP family, transduces TRAF2-induced ASK1-JNK activation
HF Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Catalase, but not MnSOD, inhibits gluc deprivation-activated ASK1-MEK-MAPK signal transduction pathway and prevents relocalization of Daxx: Hydrogen peroxide as a major second messenger of metabolic oxidative stress
JJ Song et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2003)
Differential role of glutaredoxin and thioredoxin in metabolic oxidative stress-induced activation of apoptosis signal-regulating kinase 1
JJ Song et al.
BIOCHEMICAL JOURNAL (2003)
Role of glutaredoxin in metabolic oxidative stress -: Glutaredoxin as a sensor of oxidative stress mediated by H2O2
JJ Song et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Heat shock protein Hsp72 is a negative regulator of apoptosis signal-regulating kinase 1
HS Park et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Activation of the p38 signaling pathway by heat shock involves the dissociation of glutathione S-transferase Mu from Ask1
S Dorion et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Thioredoxin promotes ASK1 ubiquitination and degradation to inhibit ASK1-mediated apoptosis in a redox activity-independent manner
YM Liu et al.
CIRCULATION RESEARCH (2002)
Reversible inactivation of the tumor suppressor PTEN by H2O2
SR Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats
H Nishitoh et al.
GENES & DEVELOPMENT (2002)
Activation of apoptosis signal-regulating kinase 1 by the stress-induced activating phosphorylation of pre-formed oligomer
K Tobiume et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2002)
ASK1-Signaling promotes c-Myc protein stability during apoptosis
K Noguchi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis
K Tobiume et al.
EMBO REPORTS (2001)
Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1
AH Kim et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Activation of apoptosis signal-regulating kinase 1 (ASK1) by tumor necrosis factor receptor-associated factor 2 requires prior dissociation of the ASK1 inhibitor thioredoxin
H Liu et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)