相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Analyses of the Effects of All Ubiquitin Point Mutants on Yeast Growth Rate
Benjamin P. Roscoe et al.
JOURNAL OF MOLECULAR BIOLOGY (2013)
Protein Insertions and Deletions Enabled by Neutral Roaming in Sequence Space
Agnes Toth-Petroczy et al.
MOLECULAR BIOLOGY AND EVOLUTION (2013)
Protein Quality Control Acts on Folding Intermediates to Shape the Effects of Mutations on Organismal Fitness
Shimon Bershtein et al.
MOLECULAR CELL (2013)
Efficient translation initiation dictates codon usage at gene start
Kajetan Bentele et al.
MOLECULAR SYSTEMS BIOLOGY (2013)
The genetic code constrains yet facilitates Darwinian evolution
Elad Firnberg et al.
NUCLEIC ACIDS RESEARCH (2013)
Capturing the mutational landscape of the beta-lactamase TEM-1
Herve Jacquier et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Activity-enhancing mutations in an E3 ubiquitin ligase identified by high-throughput mutagenesis
Lea M. Starita et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
The Innate Growth Bistability and Fitness Landscapes of Antibiotic-Resistant Bacteria
J. Barrett Deris et al.
SCIENCE (2013)
Causes and Effects of N-Terminal Codon Bias in Bacterial Genes
Daniel B. Goodman et al.
SCIENCE (2013)
Positively Charged Residues Are the Major Determinants of Ribosomal Velocity
Catherine A. Charneski et al.
PLOS BIOLOGY (2013)
CBDB: The codon bias database
Adam Hilterbrand et al.
BMC BIOINFORMATICS (2012)
Deep Sequencing of Systematic Combinatorial Libraries Reveals β-Lactamase Sequence Constraints at High Resolution
Zhifeng Deng et al.
JOURNAL OF MOLECULAR BIOLOGY (2012)
The spatial architecture of protein function and adaptation
Richard N. McLaughlin et al.
NATURE (2012)
Optimization of affinity, specificity and function of designed influenza inhibitors using deep sequencing
Timothy A. Whitehead et al.
NATURE BIOTECHNOLOGY (2012)
PFunkel: Efficient, Expansive, User-Defined Mutagenesis
Elad Firnberg et al.
PLOS ONE (2012)
Critical features for biosynthesis, stability, and functionality of a G protein-coupled receptor uncovered by all-versus-all mutations
Karola M. Schlinkmann et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Soluble oligomerization provides a beneficial fitness effect on destabilizing mutations
Shimon Bershtein et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Small changes in enzyme function can lead to surprisingly large fitness effects during adaptive evolution of antibiotic resistance
Katarzyna Walkiewicz et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
A fundamental protein property, thermodynamic stability, revealed solely from large-scale measurements of protein function
Carlos L. Araya et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
PoPMuSiC 2.1: a web server for the estimation of protein stability changes upon mutation and sequence optimality
Yves Dehouck et al.
BMC BIOINFORMATICS (2011)
Synonymous but not the same: the causes and consequences of codon bias
Joshua B. Plotkin et al.
NATURE REVIEWS GENETICS (2011)
A biophysical protein folding model accounts for most mutational fitness effects in viruses
C. Scott Wylie et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
PyRosetta: a script-based interface for implementing molecular modeling algorithms using Rosetta
Sidhartha Chaudhury et al.
BIOINFORMATICS (2010)
On Relevance of Codon Usage to Expression of Synthetic and Natural Genes in Escherichia coli
Fran Supek et al.
GENETICS (2010)
Distribution of Fitness Effects Caused by Single-Nucleotide Substitutions in Bacteriophage f1
Joan B. Peris et al.
GENETICS (2010)
Evidence that the supE44 Mutation of Escherichia coli Is an Amber Suppressor Allele of glnX and that It Also Suppresses Ochre and Opal Nonsense Mutations
B. Singaravelan et al.
JOURNAL OF BACTERIOLOGY (2010)
High-resolution mapping of protein sequence-function relationships
Douglas M. Fowler et al.
NATURE METHODS (2010)
Mutational effects and the evolution of new protein functions
Misha Soskine et al.
NATURE REVIEWS GENETICS (2010)
Natural evolution of TEM-1 β-lactamase: experimental reconstruction and clinical relevance
Merijn L. M. Salverda et al.
FEMS MICROBIOLOGY REVIEWS (2010)
Chaperonin overexpression promotes genetic variation and enzyme evolution
Nobuhiko Tokuriki et al.
NATURE (2009)
An externally tunable bacterial band-pass filter
Takayuki Sohka et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Macromolecular modeling with Rosetta
Rhiju Das et al.
ANNUAL REVIEW OF BIOCHEMISTRY (2008)
An adaptive mutation in adenylate kinase that increases organismal fitness is linked to stability-activity trade-offs
Rafael Counago et al.
PROTEIN ENGINEERING DESIGN & SELECTION (2008)
The distribution of fitness effects of new mutations
Adam Eyre-Walker et al.
NATURE REVIEWS GENETICS (2007)
The stability effects of protein mutations appear to be universally distributed
Nobuhiko Tokuriki et al.
JOURNAL OF MOLECULAR BIOLOGY (2007)
Genetic constraints on protein evolution
Manel Camps et al.
CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY (2007)
Robustness-epistasis link shapes the fitness landscape of a randomly drifting protein
Shimon Bershtein et al.
NATURE (2006)
Darwinian evolution can follow only very few mutational paths to fitter proteins
DM Weinreich et al.
SCIENCE (2006)
The genetic theory of adaptation: A brief history
HA Orr
NATURE REVIEWS GENETICS (2005)
Missense meanderings in sequence space: A biophysical view of protein evolution
MA DePristo et al.
NATURE REVIEWS GENETICS (2005)
Evolution of the serine β-lactamases:: past, present and future
BG Hall et al.
DRUG RESISTANCE UPDATES (2004)
The distribution of fitness effects caused by single-nucleotide substitutions in an RNA virus
R Sanjuán et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Between genotype and phenotype: Protein chaperones and evolvability
SL Rutherford
NATURE REVIEWS GENETICS (2003)
Evolution of an antibiotic resistance enzyme constrained by stability and activity trade-offs
XJ Wang et al.
JOURNAL OF MOLECULAR BIOLOGY (2002)
分享论文
