期刊
MOLECULAR AND CELLULAR ENDOCRINOLOGY
卷 340, 期 1, 页码 3-9出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.mce.2011.05.002
关键词
Ghrelin; Alternative splicing; Cryptein; Receptor; Peptide
资金
- National Breast Cancer Foundation
- National Health and Medical Research Council
- Cancer Council Queensland
- Faculty of Science and Technology at the Queensland University of Technology (QUT)
- Commonwealth Scientific Research Organisation (CSIRO)
- Australian Postgraduate award
- QUT
The ghrelin axis consists of the gene products of the ghrelin gene (GHRL), and their receptors, including the classical ghrelin receptor GHSR. While it is well-known that the ghrelin gene encodes the 28 amino acid ghrelin peptide hormone, it is now also clear that the locus encodes a range of other bioactive molecules, including novel peptides and non-coding RNAs. For many of these molecules, the physiological functions and cognate receptor(s) remain to be determined. Emerging research techniques, including proteogenomics, are likely to reveal further ghrelin axis-derived molecules. Studies of the role of ghrelin axis genes, peptides and receptors, therefore, promises to be a fruitful area of basic and clinical research in years to come. (c) 2011 Elsevier Ireland Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据