期刊
MOLECULAR AND CELLULAR ENDOCRINOLOGY
卷 314, 期 2, 页码 239-243出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.mce.2009.05.009
关键词
MAPK; ERK; p38; Spermatogenesis; Spermatozoa; Sperm motility
The generation of mature spermatozoa in the epididymis includes the activation of the MAPK cascade in a complex manner. MAPKs are thought to be involved in the regulation of transcription and ectoplasmic specialization (ES) in the testis. MAPKs also regulate mature spermatozoa flagellar motility, hyperactivation and the acrosome reaction. Here we review the current data regarding the functions of MAPKs in spermatogenesis and in mature spermatozoa. (C) 2009 Elsevier Ireland Ltd. All rights reserved.
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