期刊
MOLECULAR AND CELLULAR ENDOCRINOLOGY
卷 299, 期 1, 页码 14-22出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.mce.2008.09.005
关键词
Pulses; Gonadotropin; Mechanism; Deconvolution; Approximate entropy
资金
- Center for Translational Science Activities (CTSA) [1 UL 1 RR024150, RRO19991]
- National Center for Research Resources [AG23133, AG029362, DK072095, DK063609]
- National Institutes of Health
Aging results in insidious decremental changes in hypothalamic, pituitary and gonadal function. The foregoing three main anatomic loci of control are regulated by intermittent time-delayed signal exchange, principally via gonadotropin-releasing hormone (GnRH), luteinizing hormone (LH) and testosterone/estradiol (Te/E-2). A mathematical framework is required to embody these dynamics. The present review highlights integrative adaptations in the aging male hypothalamic-pituitary-gonadal axis, as assessed by recent objective ensemble models of the axis as a whole. (C) 2008 Elsevier Ireland Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据