相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。PARG is dispensable for recovery from transient replicative stress but required to prevent detrimental accumulation of poly(ADP-ribose) upon prolonged replicative stress
Giuditta Illuzzi et al.
NUCLEIC ACIDS RESEARCH (2014)
Deficiency of terminal ADP-ribose protein glycohydrolase TARG1/C6orf130 in neurodegenerative disease
Reza Sharifi et al.
EMBO JOURNAL (2013)
Oncogenes induce genotoxic stress by mitotic processing of unusual replication intermediates
Kai J. Neelsen et al.
JOURNAL OF CELL BIOLOGY (2013)
Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition
Matteo Berti et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2013)
Friedreich's ataxia-associated GAA repeats induce replication-fork reversal and unusual molecular junctions
Cindy Follonier et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2013)
Poly(ADP-ribose) binding to Chk1 at stalled replication forks is required for S-phase checkpoint activation
WooKee Min et al.
NATURE COMMUNICATIONS (2013)
A Distinct Replication Fork Protection Pathway Connects Fanconi Anemia Tumor Suppressors to RAD51-BRCA1/2
Katharina Schlacher et al.
CANCER CELL (2012)
The Intra-S Phase Checkpoint Targets Dna2 to Prevent Stalled Replication Forks from Reversing
Jiazhi Hu et al.
CELL (2012)
Inhibition of poly(ADP-ribose) glycohydrolase (PARG) specifically kills BRCA2-deficient tumor cells
Catherine Fathers et al.
CELL CYCLE (2012)
Silencing of Apoptosis-Inducing factor and poly (ADP-ribose) glycohydrolase reveals novel roles in breast cancer cell death after chemotherapy
Xiaoxing Feng et al.
MOLECULAR CANCER (2012)
New insights into the molecular and cellular functions of poly(ADP-ribose) and PARPs
Bryan A. Gibson et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
Topoisomerase I poisoning results in PARP-mediated replication fork reversal
Arnab Ray Chaudhuri et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2012)
Double-Strand Break Repair-Independent Role for BRCA2 in Blocking Stalled Replication Fork Degradation by MRE11
Katharina Schlacher et al.
CELL (2011)
The structure and catalytic mechanism of a poly(ADP-ribose) glycohydrolase
Dea Slade et al.
NATURE (2011)
PARG is recruited to DNA damage sites through poly(ADP-ribose)- and PCNA-dependent mechanisms
Oliver Mortusewicz et al.
NUCLEIC ACIDS RESEARCH (2011)
Poly(ADP-Ribose) Polymerase Inhibition: Targeted Therapy for Triple-Negative Breast Cancer
Carey K. Anders et al.
CLINICAL CANCER RESEARCH (2010)
Replication protein A: directing traffic at the intersection of replication and repair
Greg G. Oakley et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2010)
Hydroxyurea-Stalled Replication Forks Become Progressively Inactivated and Require Two Different RAD51-Mediated Pathways for Restart and Repair
Eva Petermann et al.
MOLECULAR CELL (2010)
Rad51 protects nascent DNA from Mre11-dependent degradation and promotes continuous DNA synthesis
Yoshitami Hashimoto et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2010)
Dual role of poly(ADP-ribose) glycohydrolase in the regulation of cell death in oxidatively stressed A549 cells
Katalin Erdelyi et al.
FASEB JOURNAL (2009)
Poly (ADP-ribose) glycohydrolase (PARG) and its therapeutic potential
WooKee Min et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2009)
Radiation-induced mitotic catastrophe in PARG-deficient cells
Jean-Christophe Ame et al.
JOURNAL OF CELL SCIENCE (2009)
Mono-galloyl glucose derivatives are potent poly(ADP-ribose) glycohydrolase (PARG) inhibitors and partially reduce PARP-1-dependent cell death
L. Formentini et al.
BRITISH JOURNAL OF PHARMACOLOGY (2008)
Poly ADP-ribose polymerase-1: An international molecule of mystery
Bethany C. Woodhouse et al.
DNA REPAIR (2008)
Cytotoxicity and mutagenicity of endogenous DNA base lesions as potential cause of human aging
Mansour Akbari et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2008)
Poly(ADP-ribose) polymerase 1 accelerates single-strand break repair in concert with poly(ADP-ribose) glycohydrolase
Anna E. O. Fisher et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Expandable DNA repeats and human disease
Sergei M. Mirkin
NATURE (2007)
The expanding role of poly(ADP-ribose) metabolism:: current challenges and new perspectives
JP Gagné et al.
CURRENT OPINION IN CELL BIOLOGY (2006)
Replication fork reactivation downstream of a blocked nascent leading strand
RC Heller et al.
NATURE (2006)
Multiple mechanisms control chromosome integrity after replication fork uncoupling and restart at irreparable UV lesions
M Lopes et al.
MOLECULAR CELL (2006)
Poly(ADP-ribose) glycohydrolase inhibitor as chemosensitiser of malignant melanoma for temozolomide
L Tentori et al.
EUROPEAN JOURNAL OF CANCER (2005)
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
HE Bryant et al.
NATURE (2005)
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
H Farmer et al.
NATURE (2005)
Exo1 processes stalled replication forks and counteracts fork reversal in checkpoint-defective cells
C Cotta-Ramusino et al.
MOLECULAR CELL (2005)
Failure to degrade poly(ADP-ribose) causes increased sensitivity to cytotoxicity and early embryonic lethality
DW Koh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Depletion of the 110-kilodalton isoform of poly(ADP-ribose) glycohydrolase increases sensitivity to genotoxic and endotoxic stress in mice
U Cortes et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Human poly(ADP-ribose) glycohydrolase is expressed in alternative splice variants yielding isoforms that localize to different cell compartments
ML Meyer-Ficca et al.
EXPERIMENTAL CELL RESEARCH (2004)
PARP-1, a determinant of cell survival in response to DNA damage
WJ Bouchard et al.
EXPERIMENTAL HEMATOLOGY (2003)
Functional interaction between PARP-1 and PARP-2 in chromosome stability and embryonic development in mouse
JMN de Murcia et al.
EMBO JOURNAL (2003)
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