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Cyclin-dependent kinase control of the initiation-to-elongation switch of RNA polymerase II
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The yeast regulator of transcription protein Rtr1 lacks an active site and phosphatase activity
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Distinct requirement of RNA polymerase II CTD phosphorylations in budding and fission yeast
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The RNA polymerase II C-terminal domain promotes splicing activation through recruitment of a U2AF65-Prp19 complex
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The Cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genes
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RNAP II CTD Phosphorylated on Threonine-4 Is Required for Histone mRNA 3′ End Processing
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Phosphorylation of RNAPII To P-TEFb or not to P-TEFb?
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CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1
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The Integrator Complex Recognizes a New Double Mark on the RNA Polymerase II Carboxyl-terminal Domain
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Crystal structure of the human symplekin-Ssu72-CTD phosphopeptide complex
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Gene-specific RNA polymerase II phosphorylation and the CTD code
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Chemical-genomic dissection of the CTD code
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Uniform transitions of the general RNA polymerase II transcription complex
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Pre-mRNA Processing Reaches Back to Transcription and Ahead to Translation
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TFIIH-Associated Cdk7 Kinase Functions in Phosphorylation of C-Terminal Domain Ser7 Residues, Promoter-Proximal Pausing, and Termination by RNA Polymerase II
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TFIIH Kinase Places Bivalent Marks on the Carboxy-Terminal Domain of RNA Polymerase II
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The Structure of Fcp1, an Essential RNA Polymerase II CTD Phosphatase
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RNA polymerase II pauses and associates with pre-mRNA processing factors at both ends of genes
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Transcribing RNA polymerase II is phosphorylated at CTD residue serine-7
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SCIENCE (2007)
Serine-7 of the RNA polymerase IICTD is specifically required for snRNA gene expression
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SCIENCE (2007)
Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics
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NATURE STRUCTURAL & MOLECULAR BIOLOGY (2006)
Role of the mammalian RNA polymerase IIC-terminal domain (CTD) nonconsensus repeats in CTD stability and cell proliferation
RD Chapman et al.
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Cotranscriptional spliceosome assembly occurs in a stepwise fashion and requires the cap binding complex
J Görnemann et al.
MOLECULAR CELL (2005)
Analysis of the requirement for RNA polymerase IICTD heptapeptide repeats in pre-mRNA splicing and 3′-end cleavage
E Rosonina et al.
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Phosphorylation of serine 2 within the RNA polymerase IIC-terminal domain couples transcription and 3′ end processing
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MOLECULAR CELL (2004)
Coordination of transcription, RNA processing, and surveillance by P-TEFb kinase on heat shock genes
ZY Ni et al.
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Structure and mechanism of RNA polymerase IICTD phosphatases
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MOLECULAR CELL (2004)
The last CTD repeat of the mammalian RNA polymerase II large subunit is important for its stability
RD Chapman et al.
NUCLEIC ACIDS RESEARCH (2004)
Functional interactions of RNA-capping enzyme with factors that positively and negatively regulate promoter escape by RNA polymerase II
SS Mandal et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
RNA polymerase II carboxy-terminal domain phosphorylation is required for cotranscriptional pre-mRNA splicing and 3′-end formation
G Bird et al.
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Pin1 modulates the structure and function of human RNA polymerase II
YX Xu et al.
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A 10 residue motif at the C-terminus of the RNA pol II CTD is required for transcription, splicing and 3′ end processing
N Fong et al.
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Structure of an mRNA capping enzyme bound to the phosphorylated carboxy-terminal domain of RNA polymerase II
C Fabrega et al.
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The C-terminal domain of pol II and a DRB-sensitive kinase are required for 3′ processing of U2 snRNA
JE Medlin et al.
EMBO JOURNAL (2003)
Characterization of the CTD phosphatase Fcp1 from fission yeast -: Preferential dephosphorylation of serine 2 versus serine 5
S Hausmann et al.
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Opposing effects of Ctk1 kinase and Fcp1 phosphatase at Ser 2 of the RNA polymerase II C-terminal domain
EJ Cho et al.
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Capping, splicing, and 3′ processing are independently stimulated by RNA polymerase II:: different functions for different segments of the CTD
N Fong et al.
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The splicing factor, Prp40, binds the phosphorylated carboxyl-terminal domain of RNA polymerase II
DP Morris et al.
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