4.5 Article

Ubiquitin Hydrolase UCH-L1 Destabilizes mTOR Complex 1 by Antagonizing DDB1-CUL4-Mediated Ubiquitination of Raptor

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Discovery of Specific Inhibitors of Human USP7/HAUSP Deubiquitinating Enzyme

Celine Reverdy et al.

CHEMISTRY & BIOLOGY (2012)

Article Biochemistry & Molecular Biology

mTOR-Dependent Regulation of PHLPP Expression Controls the Rapamycin Sensitivity in Cancer Cells

Jianyu Liu et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Biochemistry & Molecular Biology

Systematic and Quantitative Assessment of the Ubiquitin-Modified Proteome

Woong Kim et al.

MOLECULAR CELL (2011)

Review Cell Biology

mTOR: from growth signal integration to cancer, diabetes and ageing

Roberto Zoncu et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2011)

Article Multidisciplinary Sciences

Control of mTORC1 signaling by the Opitz syndrome protein MID1

Enbo Liu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Biochemistry & Molecular Biology

The therapeutic potential of deubiquitinating enzyme inhibitors

Frederic Colland

BIOCHEMICAL SOCIETY TRANSACTIONS (2010)

Article Biochemistry & Molecular Biology

mTOR Ser-2481 Autophosphorylation Monitors mTORC-specific Catalytic Activity and Clarifies Rapamycin Mechanism of Action

Ghada A. Soliman et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Review Public, Environmental & Occupational Health

Association Between the Ubiquitin Carboxyl-Terminal Esterase L1 Gene (UCHL1) S18Y Variant and Parkinson's Disease: A HuGE Review and Meta-Analysis

Margaret Ragland et al.

AMERICAN JOURNAL OF EPIDEMIOLOGY (2009)

Article Biochemistry & Molecular Biology

Therapeutic targeting of mTOR in tuberous sclerosis

Julian R. Sampson

BIOCHEMICAL SOCIETY TRANSACTIONS (2009)

Article Neurosciences

Rapamycin activation of 4E-BP prevents parkinsonian dopaminergic neuron loss

Luke S. Tain et al.

NATURE NEUROSCIENCE (2009)

Article Biochemical Research Methods

Intensive RNAi with lentiviral vectors in mammalian cells

Tanner Miest et al.

METHODS (2009)

Article Neurosciences

Differential effects of Usp14 and Uch-L1 on the ubiquitin proteasome system and synaptic activity

B. J. Walters et al.

MOLECULAR AND CELLULAR NEUROSCIENCE (2008)

Article Biochemistry & Molecular Biology

Reversal of learning deficits in a Tsc2+/- mouse model of tuberous sclerosis

Dan Ehninger et al.

NATURE MEDICINE (2008)

Article Multidisciplinary Sciences

The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1

Yasemin Sancak et al.

SCIENCE (2008)

Article Biochemistry & Molecular Biology

Mechanisms, biology and inhibitors of deubiquitinating enzymes

Kerry Routenberg Love et al.

NATURE CHEMICAL BIOLOGY (2007)

Review Biochemistry & Molecular Biology

DCAFs, the missing link of the CUL4-DDB1 ubiquitin ligase

Jennifer Lee et al.

MOLECULAR CELL (2007)

Article Biochemistry & Molecular Biology

PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase

Yasemin Sancak et al.

MOLECULAR CELL (2007)

Article Biochemistry & Molecular Biology

Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB

DD Sarbassov et al.

MOLECULAR CELL (2006)

Article Multidisciplinary Sciences

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

DD Sarbassov et al.

SCIENCE (2005)

Article Clinical Neurology

UCHL1 is a Parkinson's disease susceptibility gene

DM Maraganore et al.

ANNALS OF NEUROLOGY (2004)

Article Multidisciplinary Sciences

Activity-based ubiquitin-specific protease (USP) profiling of virus-infected and malignant human cells

H Ovaa et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Cell Biology

The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins

LS Harrington et al.

JOURNAL OF CELL BIOLOGY (2004)