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Increased gene copy number of ERG on chromosome 21 but not TMPRSS2-ERG fusion predicts outcome in prostatic adenocarcinomas
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TMPRSS2-ERG gene fusion is associated with low Gleason scores and not with high-grade morphological features
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ERG oncoprotein expression in prostate cancer: clonal progression of ERG-positive tumor cells and potential for ERG-based stratification
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TMPRSS2-ERG Gene Fusion Is Not Associated with Outcome in Patients Treated by Prostatectomy
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PTEN genomic deletion is associated with p-Akt and AR signalling in poorer outcome, hormone refractory prostate cancer
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Fluorescence in situ hybridization study shows association of PTEN deletion with ERG rearrangement during prostate cancer progression
Bo Han et al.
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Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate
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Characterization of TMPRSS2-ERG fusion high-grade prostatic intraepithelial neoplasia and potential clinical implications
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Chromosomal imbalances, and immunohistochemical loss of heterozygosity, expression of TP53, RB1, and PTEN in intraductal cancer, intraepithelial neoplasia, and invasive adenocarcinoma of the prostate
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ATP modulates PTEN subcellular localization in multiple cancer cell lines
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Absence of TMPRSS2:ERG fusions and PTEN losses in prostate cancer is associated with a favorable outcome
Maisa Yoshimoto et al.
MODERN PATHOLOGY (2008)
Duplication of the fusion of TMPRSS2 to ERG sequences identifies fatal human prostate cancer
G. Attard et al.
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FISH analysis of 107 prostate cancers shows that PTEN genomic deletion is associated with poor clinical outcome
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ONCOGENE (2007)
A short N-terminal sequence of PTEN controls cytoplasmic localization and is required for suppression of cell growth
G. Denning et al.
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Immunohistochemical antibody cocktail staining (p63/HMWCK/AMACR) of ductal adenocarcinoma and Gleason pattern 4 cribriform and noncribriform acinar adenocarcinomas of the prostate
Mehsati Herawi et al.
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Adjuvant weekly docetaxel for patients with high risk prostate cancer after radical prostatectomy: A multi-institutional pilot study
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Essential role for nuclear PTEN in maintaining chromosomal integrity
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Intraductal carcinoma of the prostate on needle biopsy: histologic features and clinical significance
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Interphase FISH analysis of PTEN in histologic sections shows genomic deletions in 68% of primary prostate cancer and 23% of high-grade prostatic intra-epithelial neoplasias
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The PTEN gene in locally progressive prostate cancer is preferentially inactivated by bi-allelic gene deletion
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Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer
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