期刊
MITOCHONDRION
卷 8, 期 1, 页码 61-73出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.mito.2007.10.001
关键词
mitochondria; cytochrome c; ccm; CCHL
As part of the respiratory chain, c-type cytochromes are essential electron transporters. They are characterized by the covalent attachment of a heme prosthetic group. The biogenesis of these proteins includes all the processes leading to this fixation. Yeast and animals have evolved a comparatively simple mechanism. relying on cytochrome c heme lyases. In contrast, plant mitochondria have kept a maturation pathway inherited from their prokaryote ancestor. It involves Ccm proteins encoded in both the nuclear and the mitochondrial genomes of plants. These proteins compose a heme delivery pathway, include an ABC transporter, a redox protein and a putative heme lyase. (C) 2007 Elsevier B.V. and Mitochondria Research Society. All rights reserved.
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