期刊
MINI-REVIEWS IN MEDICINAL CHEMISTRY
卷 11, 期 13, 页码 1122-1129出版社
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/138955711797655362
关键词
Berberine; structural modification; biological activities
资金
- National Natural Science Foundation of China [81072554]
Berberine is an isoquinoline alkaloid isolated from Chinese herbs such as Coptidis Rhizome. This paper is a systematic review of the structural modifications of berberine for different biological activities such as antitumor, antimicrobial, anti-Alzheimer's disease, antihyperglycemic, anti-inflammatory and antimalaria. The current review would provide some useful information for further studies on structural modification of berberine for discovering new drug leads.
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