期刊
MINI-REVIEWS IN MEDICINAL CHEMISTRY
卷 9, 期 1, 页码 60-69出版社
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/138955709787001677
关键词
AIDS; HIV-1; NF-kappa B; transcription; inhibitor; LTR; I kappa B; IKK
NF-kappaB (NF-kappa B), the transcription factors of HIV-1, play an important role in triggering HIV transcription. The inhibition of NF-kappa B activation and their signaling pathway offers a potential anti-HIV therapy strategy. This review reports the mode of action of NF-kappa B in triggering HIV-1 transcription and the status of the inhibitors.
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