期刊
MINI-REVIEWS IN MEDICINAL CHEMISTRY
卷 9, 期 11, 页码 1284-1291出版社
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/138955709789878114
关键词
Laminin-332; alpha 6 beta 4 integrin; basement membrane; extracellular matrix; tumor; cell migration; cell adhesion; ErbB2
Laminin-332 and alpha 6 beta 4 integrin is major hemidesmosome components in the skin. As many studies have shown that laminin-332 and alpha 6 beta 4 integrin play important roles in tumor progression via activation of phosphatidylinositol-3 kinase signaling, understanding of the molecular mechanisms of them could lead to a new drug for cancer therapy.
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