Polyphenols as potential inhibitors of amyloid aggregation and toxicity: Possible significance to Alzheimer's disease

Beta-amyloid (A likely plays a pivotal role in the etiology of Alzheimer's disease (AD). Consequently, A associated pathways are targets for the development of possible effective AD therapies. This review first updates strategies aimed at the inhibition of A formation and then discusses the role of food-derived polyphenols as putative anti-amyloid drugs.