期刊
MINI-REVIEWS IN MEDICINAL CHEMISTRY
卷 8, 期 13, 页码 1384-1394出版社
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/138955708786369573
关键词
Suramin; trypanosomiasis; onchocerciasis; FGF
Suramin is a polysulfonated polyaromatic symmetrical urea. It is currently used to treat African river blindness and African sleeping sickness. Suramin has also been extensively trialed recently to treat a number of other diseases, including many cancers. Here, we examine its modes of action and discuss its structure-activity relationships.
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