Magnetic cylindrical ordered mesoporous nanocarriers for targeted drug delivery

An MCM-41 type magnetic cylindrical ordered mesoporous silicon dioxide (M-COMSD) nanocarrier for targeted drug delivery has been synthesised. Pharmaceutical drug molecules have been loaded into the mesoporous framework of the M-COMSD. In vitro (Hale cells) and in vivo (mice) drug storage and release experiments of the nanocarrier have been performed. The results of the M-COMSD system demonstrate that this material could play a significant role in developing a new generation of controlled-release nanocarriers. (C) 2014 Elsevier Inc. All rights reserved.