期刊
MICROELECTRONIC ENGINEERING
卷 88, 期 8, 页码 1685-1688出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.mee.2010.12.023
关键词
Microfluidics; Self-assembled peptides; Nanostructures; Peptide tube; Peptide nanoparticle; On-chip fabrication
资金
- European Community [BeNatural/NMP4-CT-2006-033256]
- Danish Agency for Science Technology and Innovation [FTP 271-08-0968]
This study describes an integrated micro factory for the preparation of biological self-assembled peptide nanotubes and nanoparticles on a polymer chip, yielding controlled growth conditions. Self-assembled peptides constitute attractive building blocks for the fabrication of biological nanostructures due to the mild conditions of their synthesis process. This biological material can form nanostructures in a rapid way and the synthesis method is less expensive as compared to that of carbon nanotubes or silicon nanowires. The present article thus reports on the on-chip fabrication of self-assembled peptide nanostructures by means of a microfluidic device that is able to resist the harsh conditions imposed by the solvent used during the nanostructure synthesis. This on-chip fabrication was found to be simple, rapid, and convenient. (C) 2010 Elsevier B.V. All rights reserved.
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