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Uricase based methods for determination of uric acid in serum

期刊

MICROCHIMICA ACTA
卷 164, 期 1-2, 页码 1-6

出版社

SPRINGER WIEN
DOI: 10.1007/s00604-008-0044-z

关键词

Serum uric acid; Uricase; Direct kinetic uricase method; Indirect equilibrium uricase method

资金

  1. National Natural Science Foundation of China [30672009, 30700775]

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The most common methods for determination of uric acid in serum are based on the use of the enzyme uricase. Uric acid is enzymatically oxidized by oxygen to produce hydrogen peroxide, allantoin, and carbon dioxide. The four most often applied uricase methods are critically compared in this review.

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