Pattern recognition receptors in infectious skin diseases

During the last decade, multiple pattern recognition receptors (PRRs) have been identified. These are involved in the innate immune response against a plethora of pathogens. However, PRR functioning can also be detrimental, even during infections. This review discusses the current knowledge on PRRs that recognize dermatotropic pathogens, and potential therapeutical implications. (C) 2012 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.