4.6 Review

Autophagy: cellular defense to excessive inflammation

期刊

MICROBES AND INFECTION
卷 14, 期 2, 页码 119-125

出版社

ELSEVIER
DOI: 10.1016/j.micinf.2011.08.014

关键词

Autophagy; Inflammation; Autophagy-related genes; Pattern recognition receptors; Inflammasome; Cargo receptors

资金

  1. National Research Foundation of Korea (NRF)
  2. Korea Government (MEST) through Infection Signaling Network Research Center at Chungnam National University [2011-0006228]
  3. Ministry for Health, Welfare & Family Affairs, Republic of Korea [A100588]

向作者/读者索取更多资源

Autophagy can orchestrate a variety of cellular responses to dangerous stimuli. Our understanding of the physiologic roles of autophagy has recently expanded; in addition to its other roles, autophagy now appears to play an essential role in regulating inflammatory responses. This review describes recent findings concerning the roles and mechanisms of autophagy in controlling excessive inflammation. (C) 2011 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.

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