期刊
MICROBES AND INFECTION
卷 13, 期 12-13, 页码 983-991出版社
ELSEVIER
DOI: 10.1016/j.micinf.2011.06.011
关键词
Immune recognition; Systems immunology; Pathogen; Pathogen-associated molecular pattern
The immune system, to protect the body, must discriminate between the pathogenic and non-pathogenic microbes and respond to them in different ways. How the mucosal immune system manages to make this distinction is poorly understood. We suggest here that the distinction between pathogenic and non-pathogenic microbes is made by an integrated system rather than by single types of cells or single types of receptors; a systems biology approach is needed to understand immune recognition. (C) 2011 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.
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