期刊
MICROBES AND INFECTION
卷 12, 期 3, 页码 173-181出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.micinf.2009.12.001
关键词
Epstein-Barr virus; Immune-evasion; Antigen presentation; Tumour virus; Herpesvirus; Immune response
资金
- Wellcome Trust
- Medical Research Council
- Medical Research Council [G9818340B] Funding Source: researchfish
Persistent viruses have mechanisms for modulating the host immune responses that are essential for achieving a lifelong virus-host balance while minimizing the viral pathogenicity. Here we review some of the immune-modulating mechanisms evolved by the ubiquitous but potentially oncogenic Epstein-Barr virus, with particular emphasis on the molecular mechanisms of genes interfering with HLA class I antigen presentation. (C) 2009 Elsevier Masson SAS. All rights reserved.
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