期刊
MICRO & NANO LETTERS
卷 6, 期 2, 页码 70-74出版社
INST ENGINEERING TECHNOLOGY-IET
DOI: 10.1049/mnl.2010.0107
关键词
-
资金
- programme of major scientific and technological specialised project for 'significant new formulation of new drugs' [2009ZX09310-007]
- National Science Foundation of China Committee [30873180]
- PhD Programs Foundation of Ministry of Education of China [20090073120085]
- Shanghai Science and Technology Committee [0952nm03700]
Protein-loaded dextran nanoparticles were prepared by the method of freezing-induced phase separation. The average diameter of protein-loaded dextran nanoparticles prepared using this method was between 100 and 300 nm. The protein-loaded dextran nanoparticles were then microencapsulated into polylactide-co-glycolide acid (PLGA) microspheres by the solid-in-oil-in- water (S/O/W) multiple emulsion technique. The release behaviour of the microspheres showed that the method might improve the release profile and bioactivity in vitro, and also reduce initial burst and aggregation. The method will be potentially developed to solve protein-controlled release problems.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据