期刊
METHODS
卷 52, 期 1, 页码 38-50出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.ymeth.2010.06.003
关键词
Protein folding; Phi-Value; Protein families; Homologous proteins
资金
- Wellcome Trust [064417] Funding Source: Medline
The studies of the folding of structurally related proteins have proved to be a very important tool for investigating protein folding. Here we review some of the insights that have been gained from such studies. Our highlighted studies show just how such an investigation should be designed and emphasise the importance of the synergy between experiment and theory. We also stress the importance of choosing the right system carefully, exploiting the excellent structural and sequence databases at our disposal. (C) 2010 Elsevier Inc. All rights reserved.
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